2. Anti-infection
  3. SARS-CoV
  4. WU-04

WU-04 is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. WU-04 has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV).

For research use only. We do not sell to patients.

WU-04 Chemical Structure

WU-04 Chemical Structure

CAS No. : 2921711-74-0

Size Price Stock Quantity
5 mg USD 650 In-stock
10 mg USD 910 In-stock
25 mg USD 1680 In-stock
50 mg USD 2500 In-stock
100 mg USD 3500 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

WU-04 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

WU-04 is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. WU-04 has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV)[1].

Molecular Weight

526.38

Formula

C24H24BrN5O4
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(N[C@H]1CCCC[C@H]1NC2=C([N+]([O-])=O)C=C(Br)C=C2C(NC)=O)C3=CN=CC4=CC=CC=C43
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (189.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8998 mL 9.4988 mL 18.9977 mL
5 mM 0.3800 mL 1.8998 mL 3.7995 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8998 mL 9.4988 mL 18.9977 mL 47.4942 mL
5 mM 0.3800 mL 1.8998 mL 3.7995 mL 9.4988 mL
10 mM 0.1900 mL 0.9499 mL 1.8998 mL 4.7494 mL
15 mM 0.1267 mL 0.6333 mL 1.2665 mL 3.1663 mL
20 mM 0.0950 mL 0.4749 mL 0.9499 mL 2.3747 mL
25 mM 0.0760 mL 0.3800 mL 0.7599 mL 1.8998 mL
30 mM 0.0633 mL 0.3166 mL 0.6333 mL 1.5831 mL
40 mM 0.0475 mL 0.2375 mL 0.4749 mL 1.1874 mL
50 mM 0.0380 mL 0.1900 mL 0.3800 mL 0.9499 mL
60 mM 0.0317 mL 0.1583 mL 0.3166 mL 0.7916 mL
80 mM 0.0237 mL 0.1187 mL 0.2375 mL 0.5937 mL
100 mM 0.0190 mL 0.0950 mL 0.1900 mL 0.4749 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

WU-04 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WU-042921711-74-0WU04WU 04SARS-CoVSARS coronavirusAlpha SARS-CoV-2 variantsBeta SARS-CoV-2 variantsGamma SARS-CoV-2 variantsDelta SARS-CoV-2 variantsLambda SARS-CoV-2 variantsOmicron SARS-CoV-2 variantscoronavirusesMERS-CoVInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
WU-04
Cat. No.:
HY-149535
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.