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Results for "

METTL14

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Natural
Products

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153625
    STM2120

    		METTL3 Cancer
    STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM .
    STM2120
  • HY-160415A
    WD6305 TFA

    		PROTACs Apoptosis Cancer
    WD6305 TFA is a potent METTL3-targeted PROTAC degrader. WD6305 TFA selectively reduces the METTL3 and METTL14 complex. WD6305 TFA inhibits m 6A modification and the proliferation of AML cells and promotes apoptosis. WD6305 TFA can be used for the research of leukemic .
    WD6305 TFA
  • HY-19528
    SAH
    5+ Cited Publications

    SAH (S-Adenosylhomocysteine)

    		 Endogenous Metabolite Metabolic Disease
    SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM .
    SAH
  • HY-RS08355
    METTL14 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    METTL14 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    METTL14 Human Pre-designed siRNA Set A
    METTL14 Human Pre-designed siRNA Set A
  • HY-160415
    WD6305

    		PROTACs Apoptosis Cancer
    WD6305 is a potent METTL3-targeted PROTAC degrader. WD6305 selectively reduces the METTL3 and METTL14 complex. WD6305 inhibits m 6A modification and the proliferation of AML cells and promotes apoptosis. WD6305 can be used for the research of leukemic .
    WD6305
  • HY-151924
    Antiviral agent 23

    		Enterovirus Infection
    Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection .
    Antiviral agent 23
  • HY-151926
    Antiviral agent 24

    		Enterovirus Infection
    Antiviral agent 24 is a potent antiviral agent with EC50 values of 0.101, 19.9, 91.2 µM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner .
    Antiviral agent 24
  • HY-19528S
    SAH-d4

    SAH (S-Adenosylhomocysteine)-d4

    		 Endogenous Metabolite Metabolic Disease
    SAH-d4 is the deuterium labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM[2].
    SAH-d4
  • HY-19528S1
    SAH-13C5

    SAH (S-Adenosylhomocysteine)-13C5

    		 Endogenous Metabolite Metabolic Disease
    SAH- 13C5 is the 13C-labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM[2].
    SAH-13C5
  • HY-19528S2
    SAH-13C10

    		Endogenous Metabolite Metabolic Disease
    SAH- 13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].
    SAH-13C10
  • HY-162282
    PROTAC METTL3-14 degrader 1

    		DNA Methyltransferase Cancer
    PROTAC METTL3-14 degrader 1 (compound 30) is a PROTAC degrader of METTL3-14. PROTAC METTL3-14 degrader 1 shows a 50% or higher degradation of METTL3 and/or METTL14 .
    PROTAC <em>METTL</em>3-<em>14</em> degrader 1

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