1. Epigenetics
  2. DNA Methyltransferase
  3. PROTAC METTL3-14 degrader 1

PROTAC METTL3-14 degrader 1 (compound 29) is a PROTAC degrader of METTL3-14. PROTAC METTL3-14 degrader 1 shows a 50% or higher degradation of METTL3 and/or METTL14.

For research use only. We do not sell to patients.

PROTAC METTL3-14 degrader 1 Chemical Structure

PROTAC METTL3-14 degrader 1 Chemical Structure

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Description

PROTAC METTL3-14 degrader 1 (compound 29) is a PROTAC degrader of METTL3-14. PROTAC METTL3-14 degrader 1 shows a 50% or higher degradation of METTL3 and/or METTL14[1].

Molecular Weight

981.14

Formula

C51H66F2N12O6

SMILES

CC1(C)CCN(CC2=C(F)C=C(N3CC4(CCN(C5=CC(NCCN6CCN(C(CCCCCNC7=C(C(N(C8CCC(NC8=O)=O)C9=O)=O)C9=CC=C7)=O)CC6)=NC=N5)CC4)NC(C3)=O)C(F)=C2)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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PROTAC METTL3-14 degrader 1 Related Classifications

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  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PROTAC METTL3-14 degrader 1
Cat. No.:
HY-162282
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