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NVP (Standard)

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10224R
    Panobinostat (Standard)
    80+ Cited Publications

    LBH589 (Standard); NVP-LBH589 (Standard)

    		 Reference Standards HDAC Autophagy HIV Apoptosis Infection Cancer
    Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat (HY-10224). This product is intended for research and analytical applications. Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities . Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells . Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma .
    Panobinostat (Standard)
  • HY-10570R
    Nevirapine (Standard)

    BI-RG 587 (Standard); NSC 641530 (Standard); NVP (Standard)

    		 Reference Standards HIV Reverse Transcriptase Parasite Infection Cancer
    Nevirapine (Standard) is the analytical standard of Nevirapine. This product is intended for research and analytical applications. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM .
    Nevirapine (Standard)
  • HY-15174R
    Dactolisib Tosylate (Standard)

    BEZ235 Tosylate (Standard); NVP-BEZ 235 Tosylate (Standard)

    		 PI3K mTOR Autophagy Reference Standards Cancer
    Dactolisib (Tosylate) (Standard) is the analytical standard of Dactolisib (Tosylate). This product is intended for research and analytical applications. Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
    Dactolisib Tosylate (Standard)
  • HY-14291R
    Vildagliptin (Standard)

    LAF237 (Standard); NVP-LAF 237 (Standard)

    		 Reference Standards Dipeptidyl Peptidase Ferroptosis Apoptosis Metabolic Disease
    Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
    Vildagliptin (Standard)
  • HY-16582AR
    Sonidegib (Standard)

    Erismodegib (Standard); LDE225 (Standard); NVP-LDE225 (Standard)

    		 Smo Reference Standards Cancer
    Sonidegib (Standard) is the analytical standard of Sonidegib. This product is intended for research and analytical applications. Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .
    Sonidegib (Standard)
  • HY-13203R
    NVP-TAE 226 (Standard)

    TAE226 (Standard)

    		 FAK Pyk2 IGF-1R Insulin Receptor Apoptosis Reference Standards Endocrinology Cancer
    NVP-TAE 226 (Standard) is the analytical standard of NVP-TAE 226. This product is intended for research and analytical applications. NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively .
    NVP-TAE 226 (Standard)
  • HY-13311AR
    Infigratinib phosphate (Standard)

    BGJ-398 phosphate (Standard); NVP-BGJ398 phosphate (Standard)

    		 FGFR Reference Standards Cancer
    Infigratinib phosphate (Standard) is the analytical standard of Infigratinib phosphate. This product is intended for research and analytical applications. Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) is a potent inhibitor of the FGFR family with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
    Infigratinib phosphate (Standard)
  • HY-13311R
    Infigratinib (Standard)

    BGJ-398 (Standard); NVP-BGJ398 (Standard)

    		 FGFR Apoptosis Reference Standards Cancer
    Infigratinib (Standard) is the analytical standard of Infigratinib. This product is intended for research and analytical applications. Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
    Infigratinib (Standard)
  • HY-70063R
    Buparlisib (Standard)

    BKM120 (Standard); NVP-BKM120 (Standard)

    		 PI3K Apoptosis Reference Standards Cancer
    Buparlisib (Standard) is the analytical standard of Buparlisib. This product is intended for research and analytical applications. Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively.
    Buparlisib (Standard)
  • HY-15180R
    Buparlisib Hydrochloride (Standard)

    BKM120 Hydrochloride (Standard); NVP-BKM120 Hydrochloride (Standard)

    		 PI3K Apoptosis Reference Standards Cancer
    Buparlisib (Hydrochloride) (Standard) is the analytical standard of Buparlisib (Hydrochloride). This product is intended for research and analytical applications. Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.
    Buparlisib Hydrochloride (Standard)
  • HY-13606R
    Dacinostat (Standard)

    NVP-LAQ824 (Standard); LAQ824 (Standard)

    		 HDAC Autophagy Reference Standards Cancer
    Dacinostat (Standard) is the analytical standard of Dacinostat. This product is intended for research and analytical applications. Dacinostat is a potent HDAC inhibitor, with an IC50 of 32 nM; Dacinostat also inhibits HDAC1 with an IC50 of 9 nM, and used in cancer research.
    Dacinostat (Standard)
  • HY-10215R
    Luminespib (Standard)

    VER-52296 (Standard); AUY922 (Standard); NVP-AUY922 (Standard)

    		 Reference Standards HSP Autophagy Apoptosis Cancer
    Luminespib (Standard) is the analytical standard of Luminespib. This product is intended for research and analytical applications. Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively .
    Luminespib (Standard)
  • HY-10192R
    NVP-TAE 684 (Standard)

    TAE 684 (Standard)

    		 Reference Standards Anaplastic lymphoma kinase (ALK) Apoptosis Cancer
    NVP-TAE 684 (Standard) is the analytical standard of NVP-TAE 684 (HY-10192). This product is intended for research and analytical applications. NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM .
    NVP-TAE 684 (Standard)
  • HY-10252R
    NVP-ADW742 (Standard)

    ADW742 (Standard); GSK 552602A (Standard); ADW (Standard)

    		 Reference Standards IGF-1R Insulin Receptor Apoptosis Endocrinology Cancer
    NVP-ADW742 (Standard) is the analytical standard of NVP-ADW742 (HY-10252). This product is intended for research and analytical applications. NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells .
    NVP-ADW742 (Standard)
  • HY-16768R
    Fevipiprant (Standard)

    QAW039 (Standard); NVP-QAW039 (Standard)

    		 Prostaglandin Receptor Reference Standards Cardiovascular Disease
    Fevipiprant (Standard) is the analytical standard of Fevipiprant. This product is intended for research and analytical applications. Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma .
    Fevipiprant (Standard)
  • HY-10045R
    AEE788 (Standard)

    NVP-AEE 788 (Standard)

    		 EGFR Reference Standards Apoptosis Cancer
    AEE788 (Standard) is the analytical standard of AEE788 (HY-10045). This product is intended for research and analytical applications. AEE788 is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively.
    AEE788 (Standard)
  • HY-10224AR
    Panobinostat lactate (Standard)

    LBH589 lactate (Standard); NVP-LBH589 lactate (Standard)

    		 Reference Standards HDAC HIV Autophagy Apoptosis Infection Cancer
    Panobinostat lactate (Standard) is the analytical standard of Panobinostat lactate (HY-10224A). This product is intended for research and analytical applications. Panobinostat lactate is a potent and orally active non-selective HDAC inhibitor. Panobinostat lactate has antineoplastic activities. Panobinostat lactate effectively disrupts HIV latency. Panobinostat lactate induces cell apoptosis and autophagy. Panobinostat lactate can be used for the study of refractory or relapsed multiple myeloma .
    Panobinostat lactate (Standard)

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