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Results for "

PGK

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Recombinant Proteins

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2822
    Phosphoglycerate kinase, yeast

    PGK

    		 Endogenous Metabolite Infection Endocrinology Cancer
    Phosphoglycerate kinase, yeast (PGK), namely phosphoglycerate kinase, is a glycolytic enzyme commonly used in biochemical research. Phosphoglycerate kinase can catalyze the reversible transfer of phosphate groups from 1,3-bisphosphoglycerate (1,3-BPG) to ADP to generate 3-phosphoglycerate (3-PG) and ATP. At the same time, it can also participate in gluconeogenesis, catalyzing the opposite reaction to produce 1,3BPGA and ADP. Phosphoglycerate kinase is involved in energy metabolism, interaction with nucleic acid, tumor progression, cell death and virus replication and other related processes .
    Phosphoglycerate kinase, yeast
  • HY-W195984
    Z57346765

    		Others Cancer
    Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes in PGK1 glycolysis and inhibits PGK1-dependent cell proliferation. Z57346765 exerts inhibitory effects against clear cell renal cell carcinoma (KIRC) .
    Z57346765
  • HY-134205A
    CBR-470-1
    1 Publications Verification

    		 Keap1-Nrf2 Neurological Disease Metabolic Disease
    CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP +-induced cytotoxicity through activation of the Keap1-Nrf2 cascade .
    CBR-470-1
  • HY-RS10384
    PGK1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PGK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PGK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PGK1 Human Pre-designed siRNA Set A
    PGK1 Human Pre-designed siRNA Set A
  • HY-RS10385
    PGK2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PGK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PGK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PGK2 Human Pre-designed siRNA Set A
    PGK2 Human Pre-designed siRNA Set A
  • HY-15154
    NG 52
    4 Publications Verification

    Compound 52

    		 CDK Cancer
    NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p .
    NG 52

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