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Results for "

STAT+inhibitor

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16975
    SH-4-54
    15+ Cited Publications

    		 STAT Neurological Disease Metabolic Disease Cancer
    SH-4-54 is a CNS-penetrant STAT inhibitor that binds to STAT3 and STAT5 with KDs of 300, 464 nM, respectively .
    SH-4-54
  • HY-167692
    JI069

    		STAT Others
    JI069 is a novel JAK-STAT inhibitor that demonstrates potent activity in suppressing Th1, Th2, and Th17 differentiation while promoting iTreg differentiation. JI069 effectively inhibits STAT3 activation as well as the activation of other STATs, including STAT1, STAT5, and STAT6. JI069 has shown significant therapeutic potential in alleviating symptoms of collagen-induced arthritis in mice while inhibiting cytokine production from T cells and the phosphorylation of STAT3 in synovial cells.
    JI069
  • HY-111275
    WP-1034

    		JAK STAT Apoptosis Caspase PARP Cancer
    WP-1034 is a JAK-STAT inhibitor with proapoptotic and antileukemic activity in acute myeloid leukemia (AML). WP-1034 blocks activation of Stat 3 and 5. WP-1034 induces cell cycle arrest and triggers apoptosis. WP-1034 can be used for AML research .
    WP-1034
  • HY-128450
    JAK-STAT-IN-1

    		JAK STAT Inflammation/Immunology Cancer
    JAK-STAT-IN-1 (compound 1) is a selective JAK-STAT inhibitor. JAK-STAT-IN-1 can be used for the research of autoimmune disorder .
    JAK-STAT-IN-1

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