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Results for "

SiHa

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0124
    Dioscin
    5+ Cited Publications

    Collettiside III; CCRIS 4123

    		 Autophagy Apoptosis Cancer
    Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .
    Dioscin
  • HY-101677
    cPrPMEDAP

    		Drug Metabolite Infection
    cPrPMEDAP is an intermediate metabolite of GS-9219. cpr-PMEDAP functions as a proagent of the guanine nucleotide analog PMEG and has antiproliferative activity. cPrPMEDAP is negatively charged at physiologic pH and has poor permeability into the skin .
    cPrPMEDAP
  • HY-154865
    Anticancer agent 121

    		Lactate Dehydrogenase Cancer
    Anticancer agent 121, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and can be used for anticancer research .
    Anticancer agent 121
  • HY-154866
    Anticancer agent 122

    		Lactate Dehydrogenase Cancer
    Anticancer agent 122, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and can be used for anticancer research .
    Anticancer agent 122
  • HY-13566
    Belotecan

    CKD-602 free base

    		 Topoisomerase Apoptosis Cancer
    Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer .
    Belotecan
  • HY-16160
    Cysmethynil

    		Autophagy ICMT Cancer
    Cysmethynil is an Icmt inhibitor(IC50 = 2.4 μM). Cysmethynil inhibites RAS membrane binding and EGF signal transduction. Cysmethynil prevents the cells in the G1 phase and induces autophagy. Cysmethynil inhibits PC3 cells proliferation, has synergistic effect with Paclitaxel (HY-B0015) and Doxorubicin (HY-15142A). Cysmethynil has anti-tumor effects and can be used for solid tumor (such as prostate cancer et al.) research .
    Cysmethynil
  • HY-Y1750A
    β-Aminopropionitrile hydrochloride

    BAPN hydrochloride

    		 Monoamine Oxidase Endogenous Metabolite Metabolic Disease Cancer
    β-Aminopropionitrile (BAPN) hydrochloride is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile hydrochloride targets the active site of LOX or LOXL isoenzymes .
    β-Aminopropionitrile hydrochloride

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