Anticancer agent 121
Anticancer agent 121, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and can be used for anticancer research.
For research use only. We do not sell to patients.
- CAS No.: 2924532-47-6
- Formula: C19H18N2O3S
- Molecular Weight:354.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Anticancer agent 121 (Compound 8j) (0-100 μM; 72 hours) has selective inhibition in HeLa and SiHa cervical cancer cell lines and has not noticeable toxicity in human embryonic kidney cell line HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK293, HepG2, HeLa and SiHa
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Concentration:0-100 μM
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Incubation Time:72 hours
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Result:Inhibited cell growth with IC50s of 7.9 μΜ, 6.75 μΜ and 2.32 μΜ for HepG2, HeLa and SiHa cell lines.
Had not noticeable toxicity in HEK293.
Chemical Information
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CAS No. 2924532-47-6
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Molecular Weight 354.42
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Formula C19H18N2O3S
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SMILES
O=C(OC)C/N=C1SC=C(C2=CC=CC=C2)N/1C3=CC=C(OC)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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