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Results for "

Siderophores

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N11874
    Staphyloferrin A

    		Others Infection
    Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .
    Staphyloferrin A
  • HY-128525
    Enterobactin

    		Bacterial Infection Inflammation/Immunology
    Enterobactin is a bacterial siderophore that promotes iron absorption and can be used to study inflammation. Enterobactin also disrupts macrophage (MΦs) iron homeostasis and M1/M2 polarization to protect intracellular bacteria from host antimicrobial effects .
    Enterobactin
  • HY-139887
    Antibacterial agent 63

    		Bacterial Infection
    Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.
    Antibacterial agent 63
  • HY-132915
    Anti gram-positive/negative bacteria agent 1

    		Bacterial Infection
    Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.
    Anti gram-positive/negative bacteria agent 1
  • HY-148204
    Gallichrome

    		Bacterial Infection
    Gallichrome is an active peptide. Gallichrome can interact directly with the hydroxamate moieties of the siderophore. Gallichrome can be used for the research of the uptake of iron in many gram-positive and gramnegative bacteria .
    Gallichrome
  • HY-17628
    Cefiderocol
    10+ Cited Publications

    S-649266

    		 Bacterial Antibiotic Infection
    Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
    Cefiderocol
  • HY-139698
    GT-1

    LCB10-0200

    		 Others Infection
    GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.
    GT-1
  • HY-163383
    L-Ent-oxPt(IV)

    L-EOP

    		 Bacterial Infection
    L-Ent-oxPt IV (L-EOP) is a Oxaliplatin (HY-17371)-based siderophore-platinum conjugate. L-Ent-oxPt IV exhibits selectivity towards Escherichia coli and antibacterial activity through DNA damage .
    L-Ent-oxPt(IV)
  • HY-19882
    BAL-30072

    BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .
    BAL-30072
  • HY-151944
    Antibacterial agent 128

    		Bacterial Antibiotic Infection
    Antibacterial agent 128 is a siderophore analog-Ciprofloxacin (Ciprofloxacin (HY-B0356)) conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL) .
    Antibacterial agent 128
  • HY-P1997
    Ferrichrome Iron-free

    Desferrichrome; DFC; N-Desferriferrichrome

    		 Biochemical Assay Reagents Others
    Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be used as a heterosiderophore by bacteria, including Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (0.8 μM) inhibits concanavalin A-induced proliferation of mouse spleen monocytes and reduces the number of concanavalin A-stimulated CD4+ T cells expressing IL-2 receptor. It also inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.
    Ferrichrome Iron-free
  • HY-157433
    Mab-SaS-IN-1

    		Bacterial Infection
    Mab-SaS-IN-1 (compoud 1H) is Mab-SaS inhibitor with the IC50 of 2 μM. Mab-SaS-IN-1 can be used for study of antibiosis by blocking iron uptake and metabolism .
    Mab-SaS-IN-1

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