1. Anti-infection
  2. Bacterial
  3. BAL-30072

BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively.

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BAL-30072

BAL-30072 Chemical Structure

CAS No. : 941285-15-0

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Based on 1 publication(s) in Google Scholar

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Description

BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2].

IC50 & Target

MIC90: 4 μg/mL (MDR Acinetobacter spp.), 8 μg/mL (MDR P. aeruginosa)[1][2].

Molecular Weight

518.48

Formula

C16H18N6O10S2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N[C@H]1C(C)(C)N(OS(=O)(O)=O)C1=O)/C(C2=CSC(N)=N2)=N/OCC3=CC(C(O)=CN3O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (192.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9287 mL 9.6436 mL 19.2871 mL
5 mM 0.3857 mL 1.9287 mL 3.8574 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9287 mL 9.6436 mL 19.2871 mL 48.2179 mL
5 mM 0.3857 mL 1.9287 mL 3.8574 mL 9.6436 mL
10 mM 0.1929 mL 0.9644 mL 1.9287 mL 4.8218 mL
15 mM 0.1286 mL 0.6429 mL 1.2858 mL 3.2145 mL
20 mM 0.0964 mL 0.4822 mL 0.9644 mL 2.4109 mL
25 mM 0.0771 mL 0.3857 mL 0.7715 mL 1.9287 mL
30 mM 0.0643 mL 0.3215 mL 0.6429 mL 1.6073 mL
40 mM 0.0482 mL 0.2411 mL 0.4822 mL 1.2054 mL
50 mM 0.0386 mL 0.1929 mL 0.3857 mL 0.9644 mL
60 mM 0.0321 mL 0.1607 mL 0.3215 mL 0.8036 mL
80 mM 0.0241 mL 0.1205 mL 0.2411 mL 0.6027 mL
100 mM 0.0193 mL 0.0964 mL 0.1929 mL 0.4822 mL
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BAL-30072 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BAL-30072
Cat. No.:
HY-19882
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