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Sulfoximine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106376B
    DL-Buthionine-(S,R)-sulfoximine hydrochloride
    Maximum Cited Publications
    10 Publications Verification

    Buthionine Sulfoximine hydrochloride; BSO hydrochloride

    		 Ferroptosis Cancer
    DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
    DL-Buthionine-(S,R)-<em>sulfoximine</em> hydrochloride
  • HY-106376
    DL-Buthionine-(S,R)-sulfoximine
    Maximum Cited Publications
    10 Publications Verification

    Buthionine Sulfoximine; BSO

    		 Ferroptosis Cancer
    DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
    DL-Buthionine-(S,R)-<em>sulfoximine</em>
  • HY-B1692
    L-Methionine-DL-sulfoximine
    1 Publications Verification

    MSX; MSO
    L-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia.
    L-Methionine-DL-<em>sulfoximine</em>
  • HY-106376A
    L-Buthionine-(S,R)-sulfoximine
    5+ Cited Publications

    L-Buthionine Sulfoximine; L-BSO

    		 Ferroptosis Cancer
    L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
    L-Buthionine-(S,R)-<em>sulfoximine</em>
  • HY-106376C
    L-Buthionine-(S,R)-sulfoximine hydrochloride
    5+ Cited Publications

    L-Buthionine Sulfoximine hydrochloride; L-BSO hydrochloride

    		 Ferroptosis Metabolic Disease Cancer
    L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively .
    L-Buthionine-(S,R)-<em>sulfoximine</em> hydrochloride
  • HY-118504
    Sulfoxaflor

    		nAChR Neurological Disease
    Sulfoxaflor is a sulfoximine insecticide and is an agonist of nAChR1 and nAChR2 subtypes. Sulfoxaflor is used for the control of sap-feeding insects such as Myzus persicae, Aphis gossypii, Bemissia tabaci and Nilaparvata lugens .
    Sulfoxaflor
  • HY-19323A
    (S)-Ceralasertib
    1 Publications Verification

    (S)-AZD6738

    		 ATM/ATR Cancer
    (S)-Ceralasertib ((S)-AZD6738) is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2.578 nM . (S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidine ATR inhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. (S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition .
    (S)-Ceralasertib

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