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Results for "

UVA irradiation

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164159
    α-Glucosylrutin

    		Reactive Oxygen Species (ROS) MMP Inflammation/Immunology
    α-Glucosylrutin, a flavonoid, is a potent antioxidant with free radical scavenging activity. α-Glucosylrutin reduces MMP-1 gene expression, protein expression, and enzyme activity, and reduces MMP-2 protein expression and enzyme activity in UVA-irradiated human dermal fibroblasts. α-Glucosylrutin prevents oxidative stress-induced intracellular tyrosine residue phosphorylation and counteracts intracellular thiol level depletion in human skin cells. α-Glucosylrutin is effective in the prevention of dermatologic diseases in which oxidative stress is of pathogenetic relevance, e.g. in polymorphous light eruption (PLE). α-Glucosylrutin can be used for the research of UV-induced skin photodamage/photoaging .
    α-Glucosylrutin
  • HY-109654
    Ensulizole

    		Reactive Oxygen Species (ROS) Metabolic Disease
    Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole
  • HY-W997836
    4-Amino-3-hydroxyphenylalanine

    4-AHP

    		 Endogenous Metabolite Cancer
    4-Amino-3-hydroxyphenylalanine dihydrochloride (4-AHP) is a photodegradation product of eumelanin. 4-Amino-3-hydroxyphenylalanine dihydrochloride can be used to investigate the development of cutaneous melanoma and age-related macular degeneration .
    4-Amino-3-hydroxyphenylalanine
  • HY-W745164
    3,3′-Bisdemethylpinoresinol

    		MMP Inflammation/Immunology
    3,3′-Bisdemethylpinoresinol, lignin, is a nature product and has MMP-1 inhibitory activity in UVA-irradiated human dermal fibroblasts. 3,3′-Bisdemethylpinoresinol can be isolated from the seeds of Morinda citrifolia .
    3,3′-Bisdemethylpinoresinol
  • HY-109654R
    Ensulizole (Standard)

    		Reference Standards Reactive Oxygen Species (ROS) Metabolic Disease
    Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole (Standard)
  • HY-123615
    SPD-2

    		Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology
    SPD-2 is a photo-controlled hydrogen sulfide (H2S) donor that can generate hydrogen sulfide (H2S) upon UVA irradiation (325-385 nm). SPD-2 enables photo-controlled, site-specific H2S release in living cells .
    SPD-2
  • HY-W720550
    5,6-Epoxyretinyl palmitate

    5,6-Epoxy-RP

    		 DNA/RNA Synthesis Drug Metabolite Cancer
    5,6-Epoxyretinyl palmitate (5,6-Epoxy-RP) is one of the main photodegradation products of Retinyl palmitate (HY-B1384) produced under UVA light irradiation. 5,6-Epoxyretinyl palmitate exhibits phototoxicity to cells and causes significant DNA single-strand breaks, DNA damage, and chromosomal mutations under light conditions .
    5,6-Epoxyretinyl palmitate

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