1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. Ensulizole

Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation.

For research use only. We do not sell to patients.

Ensulizole Chemical Structure

Ensulizole Chemical Structure

CAS No. : 27503-81-7

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
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500 mg USD 140 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation[1].

In Vitro

At 4.0 mM [H2O2]0, a complete removal of 40.0 μM parent PBSA and 25% decrease in TOC are achieved with 190 min of UV irradiation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

274.30

Formula

C13H10N2O3S

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=S(C1=CC=C2N=C(C3=CC=CC=C3)NC2=C1)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

0.1 M NaOH : 10 mg/mL (36.46 mM; ultrasonic and adjust pH to 8 with NaOH)

DMSO : 8.33 mg/mL (30.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6456 mL 18.2282 mL 36.4564 mL
5 mM 0.7291 mL 3.6456 mL 7.2913 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / 0.1 M NaOH 1 mM 3.6456 mL 18.2282 mL 36.4564 mL 91.1411 mL
5 mM 0.7291 mL 3.6456 mL 7.2913 mL 18.2282 mL
10 mM 0.3646 mL 1.8228 mL 3.6456 mL 9.1141 mL
15 mM 0.2430 mL 1.2152 mL 2.4304 mL 6.0761 mL
20 mM 0.1823 mL 0.9114 mL 1.8228 mL 4.5571 mL
25 mM 0.1458 mL 0.7291 mL 1.4583 mL 3.6456 mL
30 mM 0.1215 mL 0.6076 mL 1.2152 mL 3.0380 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ensulizole
Cat. No.:
HY-109654
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