Search Result
Results for "
UV
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-140920
-
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PROTAC Linkers
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Cancer
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UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
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- HY-B0966
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Benzophenone-8; UV-24
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Biochemical Assay Reagents
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Others
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Dioxybenzone is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.
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-
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- HY-U00160
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SP187
2 Publications Verification
MON-DNJ; UV4
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Flavivirus
Dengue virus
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Infection
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SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
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-
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- HY-140927
-
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UV Cleavable Biotin-PEG2-alkyne
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PROTAC Linkers
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Cancer
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Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C3-UV-biotin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-B0966R
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Benzophenone-8 (Standard); UV-24 (Standard)
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Biochemical Assay Reagents
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Others
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Dioxybenzone (Standard) is the analytical standard of Dioxybenzone. This product is intended for research and analytical applications. Dioxybenzone is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation.
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-
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- HY-B0966S
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-
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- HY-N3265
-
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MSA
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Others
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Others
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Methyl sinapate (MSA), a hydroxycinnamic acid, is a natural UV screening agent .
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- HY-109654
-
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Reactive Oxygen Species
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Metabolic Disease
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Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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- HY-N6599
-
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3-O-Feruloylquinic acid
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Others
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Others
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3-Feruloylquinic acid, a derivative of quinic acid-bound phenolic acid, shows antioxidant activity. 3-Feruloylquinic acid markedly enhances by high photosynthetically active radiation (PAR) and UV irradiances .
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- HY-D0853
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DiAzKs
1 Publications Verification
H-L-Photo-lysine
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Fluorescent Dye
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Others
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DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe .
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- HY-D0853A
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H-L-Photo-lysine hydrochloride
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Fluorescent Dye
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Others
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DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe .
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- HY-155996
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PI3K
Apoptosis
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Cancer
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FD2157 is a photosensitive PI3K inhibitor, with IC50s of 43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ respectively. FD2157 potently inhibits cancer cell proliferation and induces cell apoptosis when exposed to 365 nm UV light .
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- HY-A0067
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Benzophenone 3
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RAR/RXR
Autophagy
Apoptosis
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Neurological Disease
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Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .
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- HY-N0428
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Apoptosis
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Cancer
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Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage .
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- HY-143498
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DNA/RNA Synthesis
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Cancer
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ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC50 value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells .
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- HY-B0897
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-
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- HY-109656
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DHHB
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Others
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Others
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Diethylamino hydroxybenzoyl hexyl benzoate is a photostable UV-A absorber.
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- HY-W011954
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- HY-17587
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4-MBC; Enzacamene
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Apoptosis
PI3K
Akt
ERK
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Metabolic Disease
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4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
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- HY-A0087
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Biochemical Assay Reagents
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Others
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Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
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- HY-109654R
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Reactive Oxygen Species
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Metabolic Disease
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Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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- HY-B1023
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- HY-109655
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- HY-B1556
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NSC 6647
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Benzyl salicylate is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.
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- HY-D0114
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- HY-101897
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Fura-2 Acetoxymethyl ester
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Fluorescent Dye
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Others
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Fura-2 AM is a high affinity, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ indicator.
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-
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- HY-W099730
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Tinosorb S
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Others
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Others
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Bemotrizinol (Tinosorb S), an ultraviolet (UV) filter, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation .
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- HY-N3491
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Others
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Others
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Isodictamnine is a phototoxic furoquinoline compound of the Turnipaceae family. Isodictamnine is phototoxic to certain bacteria and yeasts under long-wave UV light .
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- HY-113485
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Melanin
1 Publications Verification
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Endogenous Metabolite
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Others
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Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.
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- HY-N10474
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Bacterial
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Others
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Obtusalin is a triterpenoid found in R. dauricum for the first time and shows UV absorption at 210 nm. Obtusalin has some antibacterial activity .
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- HY-130189
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Drug Metabolite
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Others
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S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay .
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- HY-D1200
-
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Solvent Green 1
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Fungal
Parasite
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Others
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Malachite Green Carbinol base (MGOH, MGCB) is a derivative of Malachite green (MG) with not fluorescence. Malachite green carbinol base (MGOH, MGCB), as a pH regulation reagent，MGCB molecule could release OH - under UV light irradiation and generate a progressive shift in pH values. MGCB solution turns from colorless to deep green rapidly when exposed to a high-pressure UV lamp (500 W, 50 W/cm) .
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- HY-19700
-
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MEK
ERK
Endogenous Metabolite
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Others
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trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
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- HY-W749966
-
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Isotope-Labeled Compounds
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Metabolic Disease
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Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .
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-
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- HY-B0928S
-
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Homomenthyl salicylate-d4
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Isotope-Labeled Compounds
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Others
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Homosalate-d4 is the deuterium labeled Homosalate. Homosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage.
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- HY-B0928
-
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Homomenthyl salicylate
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Biochemical Assay Reagents
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Others
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Homosalate (Homomenthyl salicylate) is an organic compound used as a sunscreen to filter UV rays and protect the skin from sun damage. Homosalate has anti-inflammatory activity .
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- HY-155754
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ATP Synthase
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Others
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3’-Acetate-ATP, an ATP analogue, is ATP acetylation product with an maxima uv absorption at 259 nm in water at neutral pH. 3’-Acetate-ATP exerts a blocking effect on nucleic acid polymerization .
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- HY-103427
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Dopamine Receptor
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Neurological Disease
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NPEC-caged-dopamine is a caged version of dopamine. NPEC-caged-Dopamine was used by applying focal photolysis with UV light (360 nm) to releases dopamine, which leads to D1 receptor activation .
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- HY-N4096
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Others
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Inflammation/Immunology
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Tsugaric acid A can significantly inhibit superoxide anion formation. Tsugaric acid A also protects human keratinocytes against damage induced by ultraviolet B (UV B) light. Tsugaric acid A can protect keratinocytes from photodamage.
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- HY-W014223S1
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Ultraviolet absorber UV-0-d5
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Isotope-Labeled Compounds
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Others
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(2,4-Dihydroxyphenyl)(phenyl)methanone-d5 is the deuterium labeled (2,4-Dihydroxyphenyl)(phenyl)methanone[1].
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- HY-W099730R
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Tinosorb S (Standard)
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Others
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Others
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Bemotrizinol (Standard) is the analytical standard of Bemotrizinol. This product is intended for research and analytical applications. Bemotrizinol (Tinosorb S), an ultraviolet (UV) filter, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation .
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- HY-B0235
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Others
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Metabolic Disease
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Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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- HY-B0235A
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Others
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Metabolic Disease
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Trichlormethiazide sodium is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide sodium increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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- HY-112356
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Others
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Others
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Scytonemin is an ultraviolet sunscreen pigment, that can be isolated from the sheaths of cyanobacteria. Scytonemin displays multiple roles, functioning as a potent UV sunscreen and antioxidant molecules, and can be exploited in cosmetic and other industries for the development of new cosmeceuticals .
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- HY-W014837
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3-(1-Pyridinio)-1-propanesulfonate
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Biochemical Assay Reagents
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Others
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NDSB-201 consists of a pyridine group attached to a propane chain, which in turn is attached to a sulfonate group. This compound is commonly used as a buffer in biochemical and biological research, especially in electrophoretic applications. It maintains a stable pH in aqueous solutions and has low UV absorption, making it suitable for use in the UV spectrum. Furthermore, due to its ability to form stable complexes with DNA and other biomolecules, 3-(pyridin-1-ium-1-yl)propane-1-sulfonate has been investigated for its potential in drug delivery and genetic research.
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- HY-19700S
-
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MEK
ERK
Endogenous Metabolite
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Others
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trans-Zeatin-d5 is deuterium labeled trans-Zeatin. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
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- HY-N5124
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Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside
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Others
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Infection
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Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid isolated from barley with antioxidant activity. In barley, phenylpropanoids have been described as having protective properties against excess UV-B radiation and have been linked to resistance to pathogens .
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- HY-B0928R
-
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Homomenthyl salicylate (Standard)
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Biochemical Assay Reagents
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Others
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Homosalate (Standard) is the analytical standard of Homosalate. This product is intended for research and analytical applications. Homosalate (Homomenthyl salicylate) is an organic compound used as a sunscreen to filter UV rays and protect the skin from sun damage. Homosalate has anti-inflammatory activity .
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- HY-135265
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Ro 12-5637
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Monoamine Oxidase
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Neurological Disease
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Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. Moclobemide N-Oxide retains certain MAO-A (monoamine oxidase) inhibitory activity, but is generally present in low concentrations. Moclobemide N-Oxide can be detected by UV absorption at 240 nm .
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- HY-D1702
-
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Fluorescent Dye
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Others
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Mag-Fura-2 tetrapotassium is a UV excitable rational fluorescent Mg 2+/Ca 2+ indicator (Ex=334-360 nm, Em=510 nm). Mag-Fura-2 tetrapotassium can be used for the determination of Mg 2+ and Ca 2+ concentrations .
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- HY-D0025
-
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Fluorescent Dye
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Others
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7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) .
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- HY-D0303A
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Solvent Orange 3 hydrochloride
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Fluorescent Dye
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Others
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Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .
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- HY-P4417A
-
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Fluorescent Dye
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Others
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Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .
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- HY-B1234
-
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Octyl methoxycinnamate
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Androgen Receptor
Estrogen Receptor/ERR
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Others
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Octinoxate (Octyl methoxycinnamate) is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
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- HY-N7681
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Taxifolin 7-O-glucoside
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Others
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Others
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Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is one of the main metabolites at the seed germination stage in Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside, a flavonoid, mainly exists in the episperm and participates in defending against pathogens and UV-damage .
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- HY-B0235R
-
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Others
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Metabolic Disease
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Trichlormethiazide (Standard) is the analytical standard of Trichlormethiazide. This product is intended for research and analytical applications. Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model .
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- HY-161160
-
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Others
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Others
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Ac4ManNDAz is a cell-permeable photocross-linking probe. Ac4ManNDAz can effectively compete with endogenous sialic acid for incorporation into cell surface glycoproteins and form cross-links with glycoprotein ligands under UV light irradiation. Ac4ManNDAz can be used to study interactions between glycoproteins .
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- HY-W034674
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Silver(1+) diethyldithiocarbamate
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Biochemical Assay Reagents
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Others
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Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.
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- HY-B0316
-
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Estrogen Receptor/ERR
Apoptosis
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Others
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Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist .
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- HY-D2083
-
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Fluorescent Dye
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Cancer
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BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments .
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- HY-B1234A
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(E)-Octyl methoxycinnamate
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Estrogen Receptor/ERR
Androgen Receptor
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Endocrinology
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(E)-Octinoxate is the isomer of Octinoxate (HY-B1234). Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
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- HY-N3616
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DNA/RNA Synthesis
Endogenous Metabolite
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Cancer
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trans-Coniferyl aldehyde (compound 2) is a natural compound isolated from the buds of clove (Syzygium aromaticum).trans-Coniferyl aldehyde suppresses 63% of the UV mutable gene expression at 1.20 μM, and with an ID50 value of 0.76 μM,and has the antimutagenic
activities against furylfuramide, Trp-P-1, and activated Trp-P-1 .
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- HY-122198
-
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Others
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Cancer
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ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation .
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- HY-113008A
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(Z)-Urocanic acid; cis-UCA
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5-HT Receptor
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Inflammation/Immunology
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cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor .
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- HY-113330
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12S-HHT
1 Publications Verification
12(S)-HHTrE
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Leukotriene Receptor
Endogenous Metabolite
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Inflammation/Immunology
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12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity .
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- HY-A0067S
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RAR/RXR
Apoptosis
Autophagy
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Neurological Disease
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Oxybenzone-d5 is the deuterium labeled Oxybenzone[1]. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[2][3][4].
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- HY-A0067R
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Benzophenone 3 (Standard)
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RAR/RXR
Autophagy
Apoptosis
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Neurological Disease
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Oxybenzone (Standard) is the analytical standard of Oxybenzone. This product is intended for research and analytical applications. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .
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- HY-D0968B
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Cyanine3 triethylamine
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Fluorescent Dye
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Others
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Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm) .
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- HY-W099538
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Dilauryl 3,3'-Thiodipropionate
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Biochemical Assay Reagents
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Others
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Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.
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- HY-B1138
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CL-82204
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COX
Caspase
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Inflammation/Immunology
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Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with analgetic and antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor .
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- HY-155730
-
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PI3K
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Cancer
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PI3K-IN-41 (compound 2) is a photocaged compound, as well as a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties. PI3K-IN-41 has potential to be used in precisely controlled cancer therapeutics. PI3K-IN-41 exhibits potent PI3K ihibition upon UV light irradiation, and enhances antitumor effect .
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- HY-B1138S
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Isotope-Labeled Compounds
COX
Caspase
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Inflammation/Immunology
|
|
Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor[1][2][3][4][5].
|
-
- HY-N5072
-
|
4',6,7-Trihydroxyisoflavone
|
CDK
PI3K
PKC
|
Cancer
|
|
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities.
Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .
|
-
- HY-W093282
-
|
Soybean oil epoxide
|
Biochemical Assay Reagents
|
Others
|
|
Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0853
-
DiAzKs
1 Publications Verification
H-L-Photo-lysine
|
Fluorescent Dyes/Probes
|
|
DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe .
|
-
- HY-D0853A
-
|
H-L-Photo-lysine hydrochloride
|
Fluorescent Dyes/Probes
|
|
DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe .
|
-
- HY-101897
-
|
Fura-2 Acetoxymethyl ester
|
Fluorescent Dyes/Probes
|
|
Fura-2 AM is a high affinity, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ indicator.
|
-
- HY-D0114
-
-
- HY-D1702
-
|
|
Fluorescent Dyes/Probes
|
|
Mag-Fura-2 tetrapotassium is a UV excitable rational fluorescent Mg 2+/Ca 2+ indicator (Ex=334-360 nm, Em=510 nm). Mag-Fura-2 tetrapotassium can be used for the determination of Mg 2+ and Ca 2+ concentrations .
|
-
- HY-D0025
-
|
|
Fluorescent Dyes/Probes
|
|
7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) .
|
-
- HY-D0303A
-
|
Solvent Orange 3 hydrochloride
|
Dyes
|
|
Chrysoidine G (Solvent Orange 3 hydrochloride) is an industrial azoic dye (cationic dye). Chrysoidine G (Solvent Orange 3 hydrochloride) is used for the construction of most textile dyestuffs and also in synthetic industrial compounds. Chrysoidine G (Solvent Orange 3 hydrochloride) concentration can be determined by UV-Vis spectroscopy .
|
-
- HY-D2083
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments .
|
-
- HY-D0968B
-
|
Cyanine3 triethylamine
|
Fluorescent Dyes/Probes
|
|
Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm) .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W014837
-
|
3-(1-Pyridinio)-1-propanesulfonate
|
Biochemical Assay Reagents
|
|
NDSB-201 consists of a pyridine group attached to a propane chain, which in turn is attached to a sulfonate group. This compound is commonly used as a buffer in biochemical and biological research, especially in electrophoretic applications. It maintains a stable pH in aqueous solutions and has low UV absorption, making it suitable for use in the UV spectrum. Furthermore, due to its ability to form stable complexes with DNA and other biomolecules, 3-(pyridin-1-ium-1-yl)propane-1-sulfonate has been investigated for its potential in drug delivery and genetic research.
|
-
- HY-W034674
-
|
Silver(1+) diethyldithiocarbamate
|
Biochemical Assay Reagents
|
|
Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.
|
-
- HY-W099538
-
|
Dilauryl 3,3'-Thiodipropionate
|
Biochemical Assay Reagents
|
|
Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.
|
-
- HY-W093282
-
|
Soybean oil epoxide
|
Biochemical Assay Reagents
|
|
Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
|
-
- HY-117134
-
|
Octyl palmitate
|
Biochemical Assay Reagents
|
|
2-Ethylhexyl palmitate is a cosmetic peptide. 2-Ethylhexyl palmitate can be used in the preparation of UV sunscreening composition .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4417A
-
|
|
Fluorescent Dye
|
Others
|
|
Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .
|
-
- HY-130189
-
|
|
Drug Metabolite
|
Others
|
|
S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay .
|
-
- HY-P5234
-
|
|
Peptides
|
Others
|
|
Tetrapeptide-26 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
|
-
- HY-P4417
-
|
|
Peptides
|
Others
|
|
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-P4323
-
|
|
Peptides
|
Others
|
|
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-P4408
-
|
|
Peptides
|
Others
|
|
Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-P4416
-
|
|
Peptides
|
Others
|
|
Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
-
- HY-P4419
-
|
|
Peptides
|
Others
|
|
Boc-Asp(OBzl)-Pro-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N6599
-
-
-
- HY-N0428
-
-
-
- HY-113485
-
-
-
- HY-N3265
-
-
-
- HY-N3491
-
-
-
- HY-N10474
-
-
-
- HY-19700
-
-
-
- HY-N4096
-
-
-
- HY-112356
-
-
-
- HY-N5124
-
-
-
- HY-B1234
-
-
-
- HY-N7681
-
-
-
- HY-N3616
-
-
-
- HY-113330
-
-
-
- HY-N5072
-
|
4',6,7-Trihydroxyisoflavone
|
Flavonoids
Classification of Application Fields
Leguminosae
Glycine max (L.) merr
Source classification
Phenols
Polyphenols
Plants
Disease Research Fields
Isoflavones
Cancer
|
CDK
PI3K
PKC
|
|
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities.
Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0966S
-
|
|
|
Dioxybenzone-d3 is deuterium labeled Dioxybenzone.
|
-
-
- HY-B0928S
-
|
|
|
Homosalate-d4 is the deuterium labeled Homosalate. Homosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage.
|
-
-
- HY-W014223S1
-
|
|
|
(2,4-Dihydroxyphenyl)(phenyl)methanone-d5 is the deuterium labeled (2,4-Dihydroxyphenyl)(phenyl)methanone[1].
|
-
-
- HY-19700S
-
|
|
|
trans-Zeatin-d5 is deuterium labeled trans-Zeatin. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
|
-
-
- HY-W749966
-
|
|
|
Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .
|
-
-
- HY-A0067S
-
|
|
|
Oxybenzone-d5 is the deuterium labeled Oxybenzone[1]. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[2][3][4].
|
-
-
- HY-B1138S
-
|
|
|
Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor[1][2][3][4][5].
|
-
| Cat. No. |
Product Name |
Application |
Reactivity |
-
- HY-P82382
-
|
DDB p48 subunit; Ddb2; DDBb; UV-DDB 2
|
WB, IHC-P, ICC/IF, FC
|
Human |
-
- HY-P80641
-
|
XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1
|
WB
|
Human, Mouse, Rat, Monkey |
|
DDB1 Antibody (YA785) is a non-conjugated and Mouse origined monoclonal antibody about 127 kDa, targeting to DDB1 (2D6). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.
|
-
- HY-P82846
-
|
RAD23A; UV excision repair protein RAD23 homolog A; HR23A; hHR23A
|
WB, FC
|
Human, Mouse, Rat |
-
- HY-P81330
-
|
RAD23B; UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58
|
WB, IHC-F, IHC-P, ICC/IF
|
Human, Mouse, Rat, Monkey, Hamster |
| Cat. No. |
Product Name |
|
Classification |
-
- HY-140920
-
|
|
|
Azide
PROTAC Synthesis
|
|
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
-
- HY-140927
-
|
UV Cleavable Biotin-PEG2-alkyne
|
|
PROTAC Synthesis
Alkynes
|
|
Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C3-UV-biotin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
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