1. PROTAC
  2. PROTAC Linker
  3. Azido-C3-UV-biotin

Azido-C3-UV-biotin (Synonyms: UV Cleavable Biotin-PEG2-alkyne)

Cat. No.: HY-140927
Handling Instructions

Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Azido-C3-UV-biotin Chemical Structure

Azido-C3-UV-biotin Chemical Structure

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Description

Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

736.87

Formula

C₃₈H₄₈N₄O₉S

SMILES

O=C1N[[email protected]@]([[email protected]]2([H])N1)([H])CS[[email protected]]2CCCCC(NCCOCCOCCNC(COC3=CC(C(C(C4=CC=CC=C4)=O)OC(CCCC#C)=O)=CC=C3)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Azido-C3-UV-biotinUV Cleavable Biotin-PEG2-alkynePROTAC LinkerInhibitorinhibitorinhibit

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Azido-C3-UV-biotin
Cat. No.:
HY-140927
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