Azido-C3-UV-biotin
Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-C3-UV-biotin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Formula: C38H48N4O9S
- Molecular Weight:736.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 736.87
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Formula C38H48N4O9S
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SMILES
O=C1N[C@@]([C@]2([H])N1)([H])CS[C@H]2CCCCC(NCCOCCOCCNC(COC3=CC(C(C(C4=CC=CC=C4)=O)OC(CCCC#C)=O)=CC=C3)=O)=O
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Synonyms
UV Cleavable Biotin-PEG2-alkyne
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)