1. Neuronal Signaling
  2. AChE
  3. 4-Methylbenzylidene camphor

4-Methylbenzylidene camphor (Synonyms: 4-MBC; Enzacamene)

Cat. No.: HY-17587 Purity: 99.86%
Handling Instructions

4-Methylbenzylidene camphor(4-MBC; Enzacamene)is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation.

For research use only. We do not sell to patients.

4-Methylbenzylidene camphor Chemical Structure

4-Methylbenzylidene camphor Chemical Structure

CAS No. : 36861-47-9

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Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 72 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 72 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 65 In-stock
Estimated Time of Arrival: December 31
1 g USD 106 In-stock
Estimated Time of Arrival: December 31
5 g USD 370 In-stock
Estimated Time of Arrival: December 31
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50 g   Get quote  

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Customer Review

Based on 5 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 4-Methylbenzylidene camphor

    4-Methylbenzylidene camphor purchased from MCE. Usage Cited in: Reprod Toxicol. 2019 Mar;84:49-58.

    PCNA protein is detected (green) and nuclei are counterstained with 4′,6-diamidino-2-phenylindole (DAPI, blue) in HTR8/SVneo cells treated with 50 μM 4-MBC for 24 h.

    4-Methylbenzylidene camphor purchased from MCE. Usage Cited in: Reprod Toxicol. 2019 Mar;84:49-58.

    4-Methylbenzylidene-camphor (4-MBC) time-dependently affects phosphorylation of protein kinases in HTR8/SVneo cells. Time-dependent phosphorylation of AKT, P70S6K, S6, GSK3β, ERK1/2, and P90RSK in response to 50 μM 4-MBC is estimated. Immunoblots are imaged to calculate normalized values by estimating the abundance of phosphorylated proteins relative to total proteins.

    4-Methylbenzylidene camphor purchased from MCE. Usage Cited in: Reprod Toxicol. 2019 Mar;84:49-58.

    4-Methylbenzylidene-camphor (4-MBC) dose-dependently affects phosphorylation of protein kinases in HTR8/SVneo cells. Concentration-dependent phosphorylation of AKT, P70S6K, S6, GSK3β, ERK1/2, and P90RSK in response to 4-MBC for 2 h is estimated. Immunoblots are imaged to calculate normalized values by estimating the abundance of phosphorylated proteins relative to total proteins.

    4-Methylbenzylidene camphor purchased from MCE. Usage Cited in: Reprod Toxicol. 2019 Mar;84:49-58.

    The effects of 4-MBC (50 μM) alone or with selective kinase inhibitors on proliferation of HTR8/SVneo cells. LY294002 (AKT inhibitor, 20 μM) and U0126 (ERK1/2 inhibitor, 20 μM) are co-treated with 4-MBC for 48 h in triplicate.
    • Biological Activity

    • Purity & Documentation

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    Description

    4-Methylbenzylidene camphor(4-MBC; Enzacamene)is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation.

    Molecular Weight

    254.37

    Formula

    C18H22O

    CAS No.
    SMILES

    CC1(C)[[email protected]@H]2CC[[email protected]]1(C)C(/C2=C\C3=CC=C(C)C=C3)=O

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 100 mg/mL (393.13 mM; Need ultrasonic)

    H2O : < 0.1 mg/mL (insoluble)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.9313 mL 19.6564 mL 39.3128 mL
    5 mM 0.7863 mL 3.9313 mL 7.8626 mL
    10 mM 0.3931 mL 1.9656 mL 3.9313 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: 2.5 mg/mL (9.83 mM); Suspended solution; Need ultrasonic

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: 2.5 mg/mL (9.83 mM); Suspended solution; Need ultrasonic

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.5 mg/mL (9.83 mM); Clear solution

    *All of the co-solvents are available by MCE.
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    This equation is commonly abbreviated as: C1V1 = C2V2

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    Product Name:
    4-Methylbenzylidene camphor
    Cat. No.:
    HY-17587
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