1. Others
    Metabolic Enzyme/Protease
  2. Estrogen Receptor/ERR
    Endogenous Metabolite
  3. Estrone

Estrone  (Synonyms: E1; Oestrone)

Cat. No.: HY-B0234 Purity: ≥98.0%
COA Handling Instructions

Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.

For research use only. We do not sell to patients.

Estrone Chemical Structure

Estrone Chemical Structure

CAS No. : 53-16-7

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Solution
10 mM * 1 mL in DMSO USD 61 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
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ready for reconstitution
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Solid
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1 g USD 66 In-stock
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5 g USD 112 In-stock
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10 g USD 185 In-stock
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50 g   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

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Description

Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Estrone is the main endogenous estrogen in postmenopausal women[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

270.37

Formula

C18H22O2

CAS No.
SMILES

C[[email protected]]1([[email protected]](CC2)([H])[[email protected]]3([H])CCC4=C(C=CC(O)=C4)[[email protected]@]3([H])CC1)C2=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (92.47 mM; ultrasonic and warming and heat to 60°C)

H2O : 0.1 mg/mL (0.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6986 mL 18.4932 mL 36.9864 mL
5 mM 0.7397 mL 3.6986 mL 7.3973 mL
10 mM 0.3699 mL 1.8493 mL 3.6986 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.5 mg/mL (9.25 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.25 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.86%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Estrone
Cat. No.:
HY-B0234
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