2. Metabolic Enzyme/Protease
  3. Steroid Sulfatase
  4. Estrone O-sulfamate

Estrone O-sulfamate  (Synonyms: Estrone 3-O-sulfamate)

Cat. No.: HY-14585
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Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer.

For research use only. We do not sell to patients.

Estrone O-sulfamate Chemical Structure

Estrone O-sulfamate Chemical Structure

CAS No. : 148672-09-7

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200 μg USD 521 Get quote 2 weeks 1 week
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Based on 1 publication(s) in Google Scholar

Other Forms of Estrone O-sulfamate:

Estrone O-sulfamate Related Antibodies

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Description

Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer[1].

In Vitro

Estrone O-sulfamate (Estrone 3-O-sulfamate) has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Estrone O-sulfamate Related Antibodies
Molecular Weight

349.44

Formula

C18H23NO4S
CAS No.
SMILES

C[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OS(N)(=O)=O)C=C4CC3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Estrone O-sulfamate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrone O-sulfamate148672-09-7Estrone 3-O-sulfamateSteroid Sulfatasesteroid sulfatase (STS)placental microsomes (P.M.)MCF-7 cellscancerInhibitorinhibitorinhibit

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