148672-09-7
Chemical Structure
Estrone O-sulfamate
Synonym(s): Estrone 3-O-sulfamate
- CAS No.: 148672-09-7
- Formula:C18H23NO4S
- Molecular Weight:349.44
IUPAC Name: (8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl sulfamate
InChIKey: RVKFQAJIXCZXQY-CBZIJGRNSA-N
SMILES: C[C@@]12[C@](CCC2=O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OS(N)(=O)=O)C=C4CC3
Biological Activity: Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Estrone O-sulfamate | 99.26% | Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer. | ||||||||||||||||||||
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