Estrone sulfate

Cat. No.: HY-113293: FAQs
Data Sheet Handling Instructions

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Estrone sulfate is an endogenous metabolite present in Blood that can be used for the research of X-Linked Ichthyosis and Obesity.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Estrone sulfate potassium and Estrone sulfate sodium) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Estrone sulfate Chemical Structure

CAS No. : 481-97-0

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Other In-stock Forms of Estrone sulfate:

Estrone sulfate potassium Estrone sulfate sodium

Other Forms of Estrone sulfate:

Estrone sulfate potassium In-stock
Estrone sulfate sodium In-stock

1 Publications Citing Use of MCE Estrone sulfate

•Cell Res. 2023 Sep 6. [Abstract]

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Biological Activity
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References
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Description

Estrone sulfate is an endogenous metabolite present in Blood that can be used for the research of X-Linked Ichthyosis and Obesity^[1]^[2]^[3].

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

350.43

Formula

C₁₈H₂₂O₅S

CAS No.

481-97-0

SMILES

C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OS(=O)(O)=O)=C4)[C@@]3([H])CC1)C2=O

Structure Classification

Steroids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [Content Brief]

[2]. Lykkesfeldt G, et al. Abnormal androgen and oestrogen metabolism in men with steroid sulphatase deficiency and recessive X-linked ichthyosis. Clin Endocrinol (Oxf). 1985 Oct;23(4):385-93. [Content Brief]

[3]. Brind J, et al. Obese men have elevated plasma levels of estrone sulfate. Int J Obes. 1990 Jun;14(6):483-6. [Content Brief]

Estrone sulfate Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estrone481-97-0Endogenous MetaboliteInhibitorinhibitorinhibit

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