Moclobemide N-Oxide
Based on 1 Customer Validation
Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide. Moclobemide N-Oxide retains certain MAO-A (monoamine oxidase) inhibitory activity, but is generally present in low concentrations. Moclobemide N-Oxide can be detected by UV absorption at 240 nm.
For research use only. We do not sell to patients.
- Purity: 99.35%
- CAS No.: 64544-24-7
- Formula: C13H17ClN2O3
- Molecular Weight:284.74
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-B0534
Moclobemide -
HY-Y0882
Hydroxylamine hydrochloride -
HY-17447A
Tranylcypromine hydrochloride -
HY-B0534R
Moclobemide (Standard) -
HY-A0091A
Pargyline -
HY-70057
Safinamide -
HY-B1018A
Phenelzine sulfate -
HY-100621
MDL 72527 -
HY-14197A
Clorgyline hydrochloride -
HY-W015490
1,4-Naphthoquinone -
HY-N2554
Osthenol -
HY-138625
PXS-5505 free base
Biological Activity
Description
IC50 & Target
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MAO-A |
Chemical Information
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CAS No. 64544-24-7
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Appearance Solid
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Molecular Weight 284.74
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Formula C13H17ClN2O3
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Color White to light yellow
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SMILES
O=C(NCC[N+]1([O-])CCOCC1)C2=CC=C(Cl)C=C2
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Synonyms
Ro 12-5637
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (87.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Rakic Ignjatovic A, et al. Moclobemide monotherapy vs. combined therapy with valproic acid or carbamazepine in depressive patients: a pharmacokinetic interaction study. Br J Clin Pharmacol. 2009 Feb;67(2):199-208. [Content Brief]
[2]. Geschke R, et al. Determination of the new monoamine oxidase inhibitor moclobemide and three of its metabolites in biological fluids by high-performance liquid chromatography. J Chromatogr. 1987 Sep 4;420(1):111-20. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.5120 mL | 17.5599 mL | 35.1198 mL | 87.7994 mL |
| 5 mM | 0.7024 mL | 3.5120 mL | 7.0240 mL | 17.5599 mL | |
| 10 mM | 0.3512 mL | 1.7560 mL | 3.5120 mL | 8.7799 mL | |
| 15 mM | 0.2341 mL | 1.1707 mL | 2.3413 mL | 5.8533 mL | |
| 20 mM | 0.1756 mL | 0.8780 mL | 1.7560 mL | 4.3900 mL | |
| 25 mM | 0.1405 mL | 0.7024 mL | 1.4048 mL | 3.5120 mL | |
| 30 mM | 0.1171 mL | 0.5853 mL | 1.1707 mL | 2.9266 mL | |
| 40 mM | 0.0878 mL | 0.4390 mL | 0.8780 mL | 2.1950 mL | |
| 50 mM | 0.0702 mL | 0.3512 mL | 0.7024 mL | 1.7560 mL | |
| 60 mM | 0.0585 mL | 0.2927 mL | 0.5853 mL | 1.4633 mL | |
| 80 mM | 0.0439 mL | 0.2195 mL | 0.4390 mL | 1.0975 mL |
Moclobemide N-Oxide Related Classifications
HY-135265 Related Classifications
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