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Results for "

Wnt3A

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Peptides

4

Recombinant Proteins

1

Antibodies

Species:
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Source:
Cat. No. Compare Product Name Species Source
  • HY-P70452
    Wnt3a Protein, Mouse (His)

    Wnt-3A; Wnt 3A; Wnt3A protein; Wnt3A

    		 Mouse E. coli
  • HY-P70453C
    Wnt3a Surrogate Protein, Human (HEK293, C-hFc)
    2 Publications Verification

    Wnt-3A; Wnt 3A; Wnt3A protein; Wnt3A

    		 Human HEK293
  • HY-P70453A
    Wnt3a Protein, Human (His)
    4 Publications Verification

    MGC119418; MGC119419; MGC119420; protein Wnt-3A; wingless-type MMTV integration site family, member 3A; Wnt3A; Wnt-3A

    		 Human E. coli
    Wnt3a protein is a ligand of Frizzled receptors and can activate TCF/LEF transcription factors in the canonical Wnt pathway. It is essential for embryonic mesoderm development, caudal somite formation, neural tube morphogenesis, and intestinal crypt stem cell self-renewal. Wnt3a Protein, Human (His) is the recombinant human-derived Wnt3a protein, expressed by E. coli , with N-6*His labeled tag. The total length of Wnt3a Protein, Human (His) is 333 a.a., with molecular weight of ~40 kDa.
  • HY-P70453B
    Wnt3a Surrogate Protein, Human (HEK293, Fc)

    Wnt3A Surrogate, Human (HEK293, Fc)

    		 Human HEK293
    Wnt3a Surrogate protein is a Wnt recombination protein that plays an important role in embryonic development, adult tissue homeostasis and injury repair. Wnt3a Surrogate protein, consisting of the domain and Fc portion of Wnt3a, helps organoids expand and maintain a source of Wnt. Organoids are a rapidly evolving model system for tissue development, and Wnt3a is considered as the essential protein for organoid growth. Wnt3a or the small molecule glycogen synthase kinase 3 (GSK3) inhibitor CHIR are commonly used as Wnt sources in experiments. However, the application of Wnt3a is hampered by Wnt lipidation, and cross-reactivity with Wnt frizzled (Fzd). Therefore, Wnt3a Surrogate protein was used instead of Wnt3a, as a water-soluble and Fzd-specific alternative Wnt agonist. And the Wnt3a Surrogate protein exhibits tissue selectivity consistent with Fzd isoform specificity. Wnt3a Surrogate Protein, Human (HEK293, Fc) is a recombinant Wnt3a protein of human origin. It is expressed by HEK293 cells with an Fc tag.

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