country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P10204

Copy Link Print Information

FZD7 antagonist 1

FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC₅₀ value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors.

For research use only. We do not sell to patients.

CAS No.: 2416664-25-8
Formula: C₁₄₂H₂₀₂N₃₂O₄₂S₄
Molecular Weight:3157.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

FZD7 antagonist 1 Chemical Structure

CAS No.: 2416664-25-8

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Wnt Isoforms :

Chemical Information

CAS No. 2416664-25-8
Molecular Weight 3157.57
Formula C₁₄₂H₂₀₂N₃₂O₄₂S₄
Sequence

Chain 1: Ac-Thr-Asp-Asp-Leu-Glu-Leu-Trp-Cys-His-Ile-Met-Tyr-NH2; Chain 2: Ac-Thr-Asp-Asp-Leu-Glu-Leu-Trp-Cys-His-Ile-Met-Tyr-NH2 (Disulfide bridge: Chain 1: Cys8-Chain 2: Cys8)
Sequence Shortening

Chain 1: Ac-TDDLELWCHIMY-NH2; Chain 2: Ac-TDDLELWCHIMY-NH2 (Disulfide bridge: Chain 1: Cys8-Chain 2: Cys8)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Simon Hansen, et al. Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate Clostridium difficile Toxin B Pathogenicity in Epithelial Cells. J Med Chem. 2019, 62, 17. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Get Quote In-stock