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Results for "

amidation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Apoptosis (1) Biochemical Assay Reagents (3) Endogenous Metabolite (2) Fungal (2) Isotope-Labeled Compounds (3) PEPCK (1) Sodium Channel (1)
By Research Areas:	Infection (1) Metabolic Disease (3) Neurological Disease (5)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0178

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride	Biochemical Assay Reagents	Others
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

HY-121205

Guineesine

Others Others

Guineesine can be isolated from Piper longum L .
HY-143923S

Belinostat amide-d5

Isotope-Labeled Compounds Others

Belinostat amide-d₅ is the deuterium labeled Belinostat amide[1].
HY-150528S

rac-Clopidogrel Amide-d4

Isotope-Labeled Compounds Others

rac-Clopidogrel Amide-d₄ is the deuterium labeled rac-Clopidogrel Amide[1].
HY-W036238S

N,N-Diisopropylnitrous amide-d14

Isotope-Labeled Compounds Others

N,N-Diisopropylnitrous amide-d₁₄ is the deuterium labeled N,N-Diisopropylnitrous amide[1].

Guineesine	Others	Others
Guineesine can be isolated from Piper longum L .

Belinostat amide-d5	Isotope-Labeled Compounds	Others
Belinostat amide-d₅ is the deuterium labeled Belinostat amide[1].

rac-Clopidogrel Amide-d4	Isotope-Labeled Compounds	Others
rac-Clopidogrel Amide-d₄ is the deuterium labeled rac-Clopidogrel Amide[1].

N,N-Diisopropylnitrous amide-d14	Isotope-Labeled Compounds	Others
N,N-Diisopropylnitrous amide-d₁₄ is the deuterium labeled N,N-Diisopropylnitrous amide[1].

HY-138126A

Dansyl-Tyr-Val-Gly TFA	Others	Neurological Disease
Dansyl-Tyr-Val-Gly TFA is a substrate of peptidylglycine monooxygenase (PHM). Peptidylglycine monooxygenase is an essential enzyme for the posttranslational amidation of neuroendocrine peptides .

HY-W721596

Pentadecanoyl ethanolamide	Endogenous Metabolite	Neurological Disease
Pentadecanoyl ethanolamide is derivate of endougenous lipid amides, the N-acylethanolamines. Pentadecanoyl ethanolamide exhibits anticonvulsant efficacy in electroshocked mice without significant toxicity .

HY-124081

N-Oleoyl-L-serine	Apoptosis	Metabolic Disease
N-Oleoyl-L-Serine is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development .

HY-128923

SKF-34288 hydrochloride 1 Publications Verification 3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride	PEPCK	Metabolic Disease
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (K_i: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .

HY-P2831

Esterase, pig liver CESs	Endogenous Metabolite	Metabolic Disease
Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .

HY-151640

Fmoc-DAP-N3	ADC Linker	Others
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies .

HY-157459

SDH-IN-11	Fungal	Infection
SDH-IN-11 (compound A7) is a SDH inhibitor, and shows inhibitory effect on nematode feeding, reproductive ability, and egg hatching. SDH-IN-11 promotes the oxidative stress of nematodes and causes intestinal damage to nematodes. SDH-IN-11 inhibits the activity of succinate dehydrogenase (SDH) in nematodes .

HY-N12122

Dehydropipernonaline	Fungal	Neurological Disease
Dehydropipernonaline (Compound 24) is an amide compound. Dehydropipernonaline shows considerable cytotoxicity to L5178Y mouse lymphoma cells (IC₅₀8.9μM). Dehydropipernonaline can be used for screening antifungal and cytotoxicity .

HY-161272

Nav1.8-IN-6	Sodium Channel	Neurological Disease
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor. The IC₅₀ values in the resting state and semi-activated state are 513.33 and 471.81 nM, respectively. Nav1.8-IN-6 has analgesic activity .

HY-W010361

Tetramethylammonium acetate	Biochemical Assay Reagents	Others
Tetramethylammonium acetate is an organic compound commonly used as a phase transfer catalyst in organic synthesis reactions, especially those involving charged species or polar reagents. It can facilitate the transfer of reactants between two immiscible phases, such as water and organic solvents, by forming stable ion pairs. Additionally, Tetramethylammonium acetate has been used to prepare a variety of organic compounds, including esters, amides, and carboxylic acids. Due to its unique physicochemical properties, it has also been investigated for its potential use in developing new materials such as ionic liquids and liquid crystals. "x" in the formula represents the number of water molecules in the crystal structure, which can vary depending on the preparation method.

HY-W250129

2,3,4,5-Tetrafluorobenzoyl chloride	Biochemical Assay Reagents	Others
2,3,4,5-Tetrafluorobenzoyl chloride is a fluorinated organic compound that belongs to the class of benzoyl chlorides. It is a colorless liquid with a pungent smell and is mainly used as an intermediate in the synthesis of various pharmaceutical and pesticide compounds. 2,3,4,5-Tetrafluorobenzoyl chloride is an acylating agent that can react with a variety of nucleophiles, including amines, alcohols, and thiols, to form amides, esters, or thioesters, respectively. Its unique fluorine-containing structure can impart desired properties to target molecules, such as increased lipophilicity or increased stability against metabolic degradation. However, due to its high reactivity and potential health hazards, proper safety measures and handling procedures must be followed when using this compound.

Cat. No.	Product Name	Type

HY-D0178

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride	Biochemical Assay Reagents
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

Biochemical Assay Reagents

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

HY-W010361

Tetramethylammonium acetate	Biochemical Assay Reagents
Tetramethylammonium acetate is an organic compound commonly used as a phase transfer catalyst in organic synthesis reactions, especially those involving charged species or polar reagents. It can facilitate the transfer of reactants between two immiscible phases, such as water and organic solvents, by forming stable ion pairs. Additionally, Tetramethylammonium acetate has been used to prepare a variety of organic compounds, including esters, amides, and carboxylic acids. Due to its unique physicochemical properties, it has also been investigated for its potential use in developing new materials such as ionic liquids and liquid crystals. "x" in the formula represents the number of water molecules in the crystal structure, which can vary depending on the preparation method.

Tetramethylammonium acetate

Biochemical Assay Reagents

Tetramethylammonium acetate is an organic compound commonly used as a phase transfer catalyst in organic synthesis reactions, especially those involving charged species or polar reagents. It can facilitate the transfer of reactants between two immiscible phases, such as water and organic solvents, by forming stable ion pairs. Additionally, Tetramethylammonium acetate has been used to prepare a variety of organic compounds, including esters, amides, and carboxylic acids. Due to its unique physicochemical properties, it has also been investigated for its potential use in developing new materials such as ionic liquids and liquid crystals. "x" in the formula represents the number of water molecules in the crystal structure, which can vary depending on the preparation method.

HY-W250129

2,3,4,5-Tetrafluorobenzoyl chloride	Biochemical Assay Reagents
2,3,4,5-Tetrafluorobenzoyl chloride is a fluorinated organic compound that belongs to the class of benzoyl chlorides. It is a colorless liquid with a pungent smell and is mainly used as an intermediate in the synthesis of various pharmaceutical and pesticide compounds. 2,3,4,5-Tetrafluorobenzoyl chloride is an acylating agent that can react with a variety of nucleophiles, including amines, alcohols, and thiols, to form amides, esters, or thioesters, respectively. Its unique fluorine-containing structure can impart desired properties to target molecules, such as increased lipophilicity or increased stability against metabolic degradation. However, due to its high reactivity and potential health hazards, proper safety measures and handling procedures must be followed when using this compound.

2,3,4,5-Tetrafluorobenzoyl chloride

Biochemical Assay Reagents

2,3,4,5-Tetrafluorobenzoyl chloride is a fluorinated organic compound that belongs to the class of benzoyl chlorides. It is a colorless liquid with a pungent smell and is mainly used as an intermediate in the synthesis of various pharmaceutical and pesticide compounds. 2,3,4,5-Tetrafluorobenzoyl chloride is an acylating agent that can react with a variety of nucleophiles, including amines, alcohols, and thiols, to form amides, esters, or thioesters, respectively. Its unique fluorine-containing structure can impart desired properties to target molecules, such as increased lipophilicity or increased stability against metabolic degradation. However, due to its high reactivity and potential health hazards, proper safety measures and handling procedures must be followed when using this compound.

Cat. No.	Product Name	Target	Research Area

HY-P2932A

Cholecystokinin-33 free acid	Peptides	Neurological Disease
Cholecystokinin-33 free acid is an analogue of Cholecystokinin (HY-P2932). C-terminal amidation is important for binding of Cholecystokinin to its receptors, and removing the amide group would decrease Cholecystokinin activity. Cholecystokinin-33 free acid can be used to study C-terminal amidation of Cholecystokinin-33 .

HY-124081

N-Oleoyl-L-serine	Apoptosis	Metabolic Disease
N-Oleoyl-L-Serine is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development .

Guineesine	Structural Classification Natural Products Piper sarmentosum Roxb. Source classification Piperaceae Plants	Others
Guineesine can be isolated from Piper longum L .

Dehydropipernonaline	Structural Classification Alkaloids Piperidine Alkaloids Source classification Piperaceae Plants Piper retrofractum Vahl	Fungal
Dehydropipernonaline (Compound 24) is an amide compound. Dehydropipernonaline shows considerable cytotoxicity to L5178Y mouse lymphoma cells (IC₅₀8.9μM). Dehydropipernonaline can be used for screening antifungal and cytotoxicity .

Belinostat amide-d5
Belinostat amide-d₅ is the deuterium labeled Belinostat amide[1].

rac-Clopidogrel Amide-d4
rac-Clopidogrel Amide-d₄ is the deuterium labeled rac-Clopidogrel Amide[1].

N,N-Diisopropylnitrous amide-d14
N,N-Diisopropylnitrous amide-d₁₄ is the deuterium labeled N,N-Diisopropylnitrous amide[1].

Cat. No.	Product Name		Classification

HY-151640

Fmoc-DAP-N3		Azide
Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies .

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amidation

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products