Guineesine
Guineesine can be isolated from Piper longum L.
For research use only. We do not sell to patients.
- CAS No.: 55038-30-7
- Formula: C24H33NO3
- Molecular Weight:383.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
0.15 mM
Compound: 9
|
Cytotoxicity against human HepG2(2.2.15) cells
Cytotoxicity against human HepG2(2.2.15) cells
|
[PMID: 23434420] |
| HepG2 2.2.15 | IC50 |
<0.05 mM
Compound: 9
|
Antiviral activity against Hepatitis B virus-infected human HepG2(2.2.15) cells assessed as inhibition of HBeAg secretion
Antiviral activity against Hepatitis B virus-infected human HepG2(2.2.15) cells assessed as inhibition of HBeAg secretion
|
[PMID: 23434420] |
| HepG2 2.2.15 | IC50 |
<0.05 mM
Compound: 9
|
Antiviral activity against Hepatitis B virus-infected human HepG2(2.2.15) cells assessed as inhibition of HBsAg secretion
Antiviral activity against Hepatitis B virus-infected human HepG2(2.2.15) cells assessed as inhibition of HBsAg secretion
|
[PMID: 23434420] |
| THP-1 | IC50 |
>50 μg/mL
Compound: 1
|
Inhibition of sICAM1/LFA1 interaction-mediated human THP1 cell adhesion after 1 hr by ELISA
Inhibition of sICAM1/LFA1 interaction-mediated human THP1 cell adhesion after 1 hr by ELISA
|
[PMID: 18672369] |
| U-937 | EC50 |
290 nM
Compound: 67
|
Inhibition of [14C]-AEA uptake in human U937 cells preincubated for 15 mins followed by [14C]-AEA addition and measured after 5 mins by scintillation counting method
Inhibition of [14C]-AEA uptake in human U937 cells preincubated for 15 mins followed by [14C]-AEA addition and measured after 5 mins by scintillation counting method
|
[PMID: 30816712] |
| WI-38 | IC50 |
8.9 μM
Compound: 3
|
Induction of senescence in human WI-38 cells
Induction of senescence in human WI-38 cells
|
[PMID: 38436272] |
Chemical Information
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CAS No. 55038-30-7
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Molecular Weight 383.52
-
Formula C24H33NO3
-
SMILES
O=C(/C=C/C=C/CCCCCC/C=C/C1=CC=C2OCOC2=C1)NCC(C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)