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Results for "

aryl radicals

" in MedChemExpress (MCE) Product Catalog:

8

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1

Biochemical Assay Reagents

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W008598
    2-Bromo-4'-fluoroacetophenone

    p-Fluorophenacyl bromide

    		 DNA/RNA Synthesis Cancer
    2-Bromo-4'-fluoroacetophenone (p-Fluorophenacyl bromide) is a photoinducible DNA cleavage inducer.2-Bromo-4'-fluoroacetophenone generates fluorine-substituted phenyl radicals upon excitation and irradiation to cleave DNA, converting circular supercoiled DNA to circular relaxed and linear DNA forms.2-Bromo-4'-fluoroacetophenone exhibits concentration-dependent DNA cleaving activity.2-Bromo-4'-fluoroacetophenone can be used for the research of cancer .
    2-Bromo-4'-fluoroacetophenone
  • HY-120976
    DEPMPO

    		Biochemical Assay Reagents Cancer
    cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds .
    DEPMPO
  • HY-W002805
    2-Bromoisonicotinic acid
    1 Publications Verification

    		 Drug Intermediate Others
    2-Bromoisonicotinic acid is a (hetero)aryl bromide building block and DNA-conjugated headpiece for photochemical C-H heteroarylation in DNA-encoded library synthesis. 2-Bromoisonicotinic acid generates a nucleophilic pyridyl radical intermediate. 2-Bromoisonicotinic acid, when conjugated to DNA, leaves electrophilic handles intact for subsequent library diversification .
    2-Bromoisonicotinic acid
  • HY-150175
    HKSOX-1

    		Fluorescent Dye Inflammation/Immunology
    HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O2 •−) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O2 •−-mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O2 •− roles in inflammation, mitochondrial stress, and other physiological processes .
    HKSOX-1
  • HY-W088188
    Co(acac)2

    Cobalt(II) acetylacetonate

    		 Biochemical Assay Reagents Others
    Co (acac)2 is an organometallic compound with catalytic activity, in which the central cobalt ion is chelated with acetylacetonate ligands. Co (acac)2 can serve as a precursor for thin films and nanomaterials, and is applicable to researches in organic synthesis, materials science, industrial applications, and other fields .
    Co(acac)2
  • HY-W800683
    4-Azide-TFP-amide-SS-Sulfo-NHS

    		Biochemical Assay Reagents Others
    4-Azide-TFP-Amide-SS-Sulfo-NHS consists of an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The NHS ester reacts with amines. The disulfide bond can be cleaved by reducing agents.
    4-Azide-TFP-amide-SS-Sulfo-NHS
  • HY-W800632
    4-Azide-TFP-amide-SS-propionic acid

    		Biochemical Assay Reagents Others
    4-Azide-TFP-Amide-SS-propionic acid contains an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond. The disulfide bond can be cleaved via reducing agents.
    4-Azide-TFP-amide-SS-propionic acid
  • HY-W800635
    4-Azide-TFP-amide-PEG4-acid

    		Biochemical Assay Reagents Others
    4-Azide-TFP-Amide-PEG4-acid contains an aryl azide and a carboxylic acid with a PEG spacer to increase aqueous solubility and decrease steric hinderance during ligation. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The carboxylic acid can be reacted with amines in the presence of an activator to form an amide bond.
    4-Azide-TFP-amide-PEG4-acid

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