2-Bromo-4'-fluoroacetophenone
Based on 1 Customer Validation
2-Bromo-4'-fluoroacetophenone (p-Fluorophenacyl bromide) is a photoinducible DNA cleavage inducer.2-Bromo-4'-fluoroacetophenone generates fluorine-substituted phenyl radicals upon excitation and irradiation to cleave DNA, converting circular supercoiled DNA to circular relaxed and linear DNA forms.2-Bromo-4'-fluoroacetophenone exhibits concentration-dependent DNA cleaving activity.2-Bromo-4'-fluoroacetophenone can be used for the research of cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.15%
- CAS 番号: 403-29-2
- 分子式: C8H6BrFO
- 分子量:217.04
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
2-Bromo-4'-fluoroacetophenone generates a reactive aryl radical after 15 min of anaerobic irradiation. This radical abstracts a deuterium atom from THF-d8 to form monodeuterated 4'-Fluoroacetophenone (HY-Y0779) with a yield of 32%[1].
2-Bromo-4'-fluoroacetophenone (0.1-100 mM; 30 min) cleaves ΦX174 RFI supercoiled DNA into nicked and linear forms in a concentration-dependent manner within 30 minutes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 403-29-2
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性状 Solid
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分子量 217.04
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分子式 C8H6BrFO
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Color Off-white to light yellow
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SMILES
BrCC(C1=CC=C(F)C=C1)=O
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別名
p-Fluorophenacyl bromide
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 66.67 mg/mL (307.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6074 mL | 23.0372 mL | 46.0745 mL | 115.1861 mL |
| 5 mM | 0.9215 mL | 4.6074 mL | 9.2149 mL | 23.0372 mL | |
| 10 mM | 0.4607 mL | 2.3037 mL | 4.6074 mL | 11.5186 mL | |
| 15 mM | 0.3072 mL | 1.5358 mL | 3.0716 mL | 7.6791 mL | |
| 20 mM | 0.2304 mL | 1.1519 mL | 2.3037 mL | 5.7593 mL | |
| 25 mM | 0.1843 mL | 0.9215 mL | 1.8430 mL | 4.6074 mL | |
| 30 mM | 0.1536 mL | 0.7679 mL | 1.5358 mL | 3.8395 mL | |
| 40 mM | 0.1152 mL | 0.5759 mL | 1.1519 mL | 2.8797 mL | |
| 50 mM | 0.0921 mL | 0.4607 mL | 0.9215 mL | 2.3037 mL | |
| 60 mM | 0.0768 mL | 0.3840 mL | 0.7679 mL | 1.9198 mL | |
| 80 mM | 0.0576 mL | 0.2880 mL | 0.5759 mL | 1.4398 mL | |
| 100 mM | 0.0461 mL | 0.2304 mL | 0.4607 mL | 1.1519 mL |
2-Bromo-4'-fluoroacetophenone 関連分類
HY-W008598 関連分類
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