HKSOX-1
Based on 3 publication(s) in Google Scholar
HKSOX-1 is a fluorescent probe for the detection and imaging of superoxide anion radicals (O2•−) with selectivity. HKSOX-1 reacts with superoxide anion radicals, cleaving the aryl triflate group to generate a free phenol and produce turn-on fluorescence. Derivative variants of HKSOX-1 include HKSOX-1r and HKSOX-1m. HKSOX-1 is applicable to studies related to endogenous superoxide detection.
For research use only. We do not sell to patients.
- CAS No.: 1786411-17-3
- Formula: C23H6F10O11S2
- Molecular Weight:712.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) HKSOX-1
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Biological Activity
Description
In Vitro
HKSOX-1 reacts rapidly and sensitively with superoxide in cell-free buffer, exhibiting a linear fluorescence response up to 13 μM with a detection limit of 23 nM[1].
HKSOX-1 exhibits excellent selectivity for superoxide in cell-free buffer, outperforming various strong oxidants and a large number of reductants[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 1786411-17-3
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Molecular Weight 712.40
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Formula C23H6F10O11S2
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SMILES
O=C(C1=CC=C2C(C(OC23C4=CC(F)=C(C(F)=C4OC5=C(C(OS(=O)(C(F)(F)F)=O)=C(C=C53)F)F)OS(=O)(C(F)(F)F)=O)=O)=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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J Hazard Mater
Mechanistic insight into airborne particulate matter PM10 as an environmental hazard for hemorrhagic stroke: Evidence from in vitro and in vivo studies. [Abstract]2024 Dec 5:480:136319. PMID: 39488980 -
Virulence
Antibacterial efficacy and mechanism of the novel antimicrobial peptide lachnospirin-1 against Acinetobacter baumannii. [Abstract]2026 Dec 31;17(1):2646808. PMID: 41838520 -
AMB Express
Repurposing pinaverium bromide against Staphylococcus and its biofilms with new mechanisms. [Abstract]2024 Dec 24;14(1):141. PMID: 39718732
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HKSOX-1 Related Classifications
HY-150175 Related Classifications
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