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Pathways Recommended: Anti-infection
Results for "

biofilm-related infections

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P5641
    Pleurocidin
    1 Publications Verification

    		 Bacterial p38 MAPK NF-κB NADH Dehydrogenase Antibiotic Infection Inflammation/Immunology
    Pleurocidin is an Antimicrobial peptide. Pleurocidin is derived from the skin mucosa or intestinal secretions of Pseudopleuronectes americanus. Pleurocidin inhibits the expression of key proteins in the MAPK and NF-κB inflammatory signaling pathways. Pleurocidin alters serum inflammatory and immune cytokine levels, regulates the down-regulation of tight junction proteins, and modulates the intestinal flora. Pleurocidin exerts antibacterial activity by inducing bacterial membrane damage, hydroxyl radical formation, and NADH depletion, and also produces a synergistic effect with Antibiotics. Pleurocidin alleviates DSS-induced ulcerative colitis. Pleurocidin can be used for research on ulcerative colitis, bacterial infections, and bacterial biofilm-related infections .
    Pleurocidin
  • HY-172132
    MurA-IN-5

    		Bacterial Infection
    MurA-IN-5 (compound 4c) exhibits (MIC) = 1.95 μg/mL against Escherichia coli and demonstrating significant potency as a MurA inhibitor with (IC50) of 3.77 μg/mL. MurA-IN-5 displays an antibiofilm activity against multiple microorganisms, indicating its potential to combat biofilm-related infections .
    MurA-IN-5
  • HY-W083821
    1-[(4-Nitrophenyl)methyl]-1,4-diazepane

    1-(4-Nitrobenzyl)-1,4-diazepane

    		 Bacterial Infection
    1-[(4-Nitrophenyl) methyl]-1,4-diazepane (1-(4-Nitrobenzyl)-1,4-diazepane) is an anti-biofilm agent. 1-[(4-Nitrophenyl) methyl]-1,4-diazepane reduces biofilm formation in Escherichia coli. 1-[(4-Nitrophenyl) methyl]-1,4-diazepane is used for the research of Escherichia coli biofilm-related infections .
    1-[(4-Nitrophenyl)methyl]-1,4-diazepane
  • HY-135223
    Chondrillasterol

    		Bacterial Infection
    Chondrillasterol is a sterol that can be isolated from Vernonia adoensis. Chondrillasterol exhibits antibacterial activity. Chondrillasterol inhibits growth of Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Chondrillasterol inhibits formation of bacterial biofilms. Chondrillasterol can be used for the research of bacterial infections .
    Chondrillasterol

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