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Cat. No.: HY-135223

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Chondrillasterol

Chondrillasterol is a sterol that can be isolated from Vernonia adoensis. Chondrillasterol exhibits antibacterial activity. Chondrillasterol inhibits growth of Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Chondrillasterol inhibits formation of bacterial biofilms. Chondrillasterol can be used for the research of bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 481-17-4
Formula: C₂₉H₄₈O
Molecular Weight:412.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chondrillasterol Chemical Structure

CAS No.: 481-17-4

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Sample (0.1mg)

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

Chondrillasterol (12.5-100 μg/mL; 20 h) inhibits the growth of Pseudomonas aeruginosa by 65%, Klebsiella pneumoniae by 38%, and Staphylococcus aureus by 25%^[1].
Chondrillasterol (50-100 μg/mL; 10 min) does not cause significant nucleic acid leakage from Pseudomonas aeruginosa^[1].
Chondrillasterol (0.4-100 μg/mL; 72 h) completely inhibits biofilm formation by Pseudomonas aeruginosa at 100 μg/mL, and causes significant inhibition at concentrations as low as 6.3 μg/mL^[1].
Chondrillasterol (0.8-100 μg/mL; 24 h) completely disrupts mature Pseudomonas aeruginosa biofilms at 1.6 μg/mL, and causes significant disruption at all tested concentrations up to 100 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 481-17-4
Molecular Weight 412.70
Formula C₂₉H₄₈O
SMILES

C[C@@]12[C@](C=3[C@@]([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])(CC1)[H])(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)C)CC)C)[H])[H]
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mozirandi W, et al. Evaluation of antimicrobial activity of chondrillasterol isolated from Vernonia adoensis (Asteraceae). BMC Complement Altern Med. 2019;19(1):249. Published 2019 Sep 6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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