carbamoyl

By Targets:	Amino Acid Derivatives (1) Endogenous Metabolite (2) Isotope-Labeled Compounds (3) Liposome (2) Melanocortin Receptor (2) NOD-like Receptor (NLR) (1) Potassium Channel (1) PROTAC Linkers (1) Somatostatin Receptor (6) Vasopressin Receptor (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (2)
Click Chemistry:	PROTAC Synthesis (1) Azide (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128425

*N-Carbamoyl-DL-aspartic acid* Ureidosuccinic Acid	Endogenous Metabolite	Metabolic Disease
N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is a precursor of nucleic acid pyrimidines .

HY-79680

*(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid*	Amino Acid Derivatives	Others
(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative .

HY-140459

*2-((Azido-PEG8-carbamoyl)methoxy)acetic acid*	PROTAC Linkers	Cancer
2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-128425A

*N-Carbamoyl-L-aspartic acid* L-Ureidosuccinic acid	Endogenous Metabolite	Others
N-Carbamoyl-L-aspartic acid is intermediate of pyrimidine (HY-Y0519) metabolism. N-Carbamoyl-L-aspartic acid can be used to measure enzyme activity of dihydroorotase (DHOse) .

HY-146716S

*N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d3 dicyclohexylamine*	Isotope-Labeled Compounds
N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d₃ (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine.

HY-149664

*3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol* DC-Chol	Liposome	Cancer
3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .

HY-136128

H3B-120	Potassium Channel	Cancer
H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC₅₀ of 1.5 μM and a K_i of 1.4 μM. H3B-120 has anti-cancer activity .

HY-P5126

DOTA-LM3	Somatostatin Receptor	Cancer
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .

HY-P5126A

DOTA-LM3 TFA	Somatostatin Receptor	Cancer
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .

HY-P5362

NODAGA-LM3	Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-P5362A

NODAGA-LM3 TFA	Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-W009418S

1-Methylnicotinamide-13C,d3 iodide	Isotope-Labeled Compounds	Others
1-Methylnicotinamide- ¹³C,d₃ (iodide) is the ¹³C- and deuterium labeled 3-Carbamoyl-1-methylpyridin-1-ium iodide[1].

HY-B0711

Carglumic Acid N-Carbamyl-L-glutamic acid	Others	Cancer
Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.

HY-125734

DMHAPC-Chol	Liposome	Others
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .

HY-P10137

Satoreotide JR11	Somatostatin Receptor	Cancer
Satoreotide (JR11) is a SSTR2 antagonist. Satoreotide is usually conjugated with radiolabeled chelators used in neuroendocrine tumor imaing .

HY-P5128

DOTA-JR11 Satoreotide tetraxetan	Somatostatin Receptor	Cancer
DOTA-JR11 is a somatostatin receptor 2 （SSTR2）antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research .

HY-113416AS

Dehydroepiandrosterone sulfate-d6 sodium dihydrate	Isotope-Labeled Compounds	Others
Dehydroepiandrosterone sulfate-d₆ (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].

HY-B0711R

Carglumic Acid (Standard) N-Carbamyl-L-glutamic acid (Standard)	Others	Cancer
Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.

HY-145087

NP3-146 NLRP3-IN-5	NOD-like Receptor (NLR)	Inflammation/Immunology
NLRP3-IN-5 is a NLRP3 inflammasome inhibitor (WO2016131098 (N-((4-chloro-2,6-dimethylphenyl)carbamoyl)-4-(2-hydroxypropan-2- l)furan-2-sulfonamide)) .

HY-P1726A

MSG606 TFA	Melanocortin Receptor
MSG606 TFA is a potent human MC1 receptor antagonist (IC₅₀=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC₅₀ values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.

HY-P1726

MSG606

Melanocortin Receptor Neurological Disease

MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects .
HY-P0041A

F992 TFA

Vasopressin Receptor Neurological Disease

F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

MSG606	Melanocortin Receptor	Neurological Disease
MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects .

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

Cat. No.	Product Name	Type

HY-149664

*3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol* DC-Chol	Drug Delivery
3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .

Cat. No.	Product Name	Target	Research Area

HY-79680

*(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid*	Amino Acid Derivatives	Others
(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative .

HY-P5126

DOTA-LM3	Somatostatin Receptor	Cancer
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .

HY-P5126A

DOTA-LM3 TFA	Somatostatin Receptor	Cancer
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5362

NODAGA-LM3	Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-P5362A

NODAGA-LM3 TFA	Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas .

HY-P10137

Satoreotide JR11	Somatostatin Receptor	Cancer
Satoreotide (JR11) is a SSTR2 antagonist. Satoreotide is usually conjugated with radiolabeled chelators used in neuroendocrine tumor imaing .

HY-P5128

DOTA-JR11 Satoreotide tetraxetan	Somatostatin Receptor	Cancer
DOTA-JR11 is a somatostatin receptor 2 （SSTR2）antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research .

HY-P10014

Bibapcitide

Peptides Cardiovascular Disease

Bibapcitide, a 26 amino acid, inhibits thrombosis .

Bibapcitide	Peptides	Cardiovascular Disease
Bibapcitide, a 26 amino acid, inhibits thrombosis .

HY-P1726A

MSG606 TFA	Melanocortin Receptor
MSG606 TFA is a potent human MC1 receptor antagonist (IC₅₀=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC₅₀ values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.

HY-P0041A

F992 TFA

Vasopressin Receptor Neurological Disease

F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-128425

*N-Carbamoyl-DL-aspartic acid* Ureidosuccinic Acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is a precursor of nucleic acid pyrimidines .

HY-128425A

*N-Carbamoyl-L-aspartic acid* L-Ureidosuccinic acid	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Carbamoyl-L-aspartic acid is intermediate of pyrimidine (HY-Y0519) metabolism. N-Carbamoyl-L-aspartic acid can be used to measure enzyme activity of dihydroorotase (DHOse) .

HY-B0711R

Carglumic Acid (Standard) N-Carbamyl-L-glutamic acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.

Cat. No.	Compare	Product Name	Species	Source

HY-P71445

	CPS1/CPSase I Protein, Human (His) carbamoyl phosphate synthase; carbamoyl phosphate synthase mitochondrial; carbamoyl phosphate synthase; carbamoyl phosphate synthetase 1; carbamoyl phosphate synthetase 1 mitochondrial; carbamoyl phosphate synthetase I; carbamoyl-phosphate synthase [ammonia]; carbamoyl-phosphate synthetase I; carbamoylphosphate synthase; carbamoylphosphate synthetase 1; carbamoylphosphate synthetase I; CPS 1; Cps1; CPSase 1; CPSase I; CPSASE1; mitochondrial; MS738	Human	E. coli
	The CPS1/CPSase I protein is critical in participating in the urea cycle and is essential for the elimination of excess ammonia in urea-bearing animals. This essential enzyme converts toxic ammonia (a byproduct of amino acid catabolism) into urea, promoting safe excretion. CPS1/CPSase I Protein, Human (His) is the recombinant human-derived CPS1/CPSase I protein, expressed by E. coli , with N-His labeled tag. The total length of CPS1/CPSase I Protein, Human (His) is 147 a.a., with molecular weight of ~20.5 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-146716S

*N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d3 dicyclohexylamine*
N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine-d₃ (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(N-methyl-carbamoyl)-L-cysteine.

HY-W009418S

1-Methylnicotinamide-13C,d3 iodide

1-Methylnicotinamide- ¹³C,d₃ (iodide) is the ¹³C- and deuterium labeled 3-Carbamoyl-1-methylpyridin-1-ium iodide[1].

1-Methylnicotinamide-13C,d3 iodide
1-Methylnicotinamide- ¹³C,d₃ (iodide) is the ¹³C- and deuterium labeled 3-Carbamoyl-1-methylpyridin-1-ium iodide[1].

HY-113416AS

Dehydroepiandrosterone sulfate-d6 sodium dihydrate
Dehydroepiandrosterone sulfate-d₆ (sodium dihydrate) is the deuterium labeled tert-Butyl N-[(1S)-1-[Methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate[1].

Cat. No.	Product Name		Classification

HY-140459

*2-((Azido-PEG8-carbamoyl)methoxy)acetic acid*		Azide PROTAC Synthesis
2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

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Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Click Chemistry

carbamoyl

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Click Chemistry

Natural
Products