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clathrin N-terminal domain

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-186018
    Pitstop 2d

    		Clathrin Infection
    Pitstop 2d is a Clathrin inhibitor with an IC50 of <2 μM. Pitstop 2d binds to Clathrin N-terminal β-propeller domain, inhibits Clathrin function and dynamics and impairs VSV entry. Pitstop 2d inhibits Clathrin-mediated Endocytosis. Pitstop 2d does not inhibit clathrin-independent Endocytosis .
    Pitstop 2d
  • HY-181933
    Clathrin-IN-5

    		Clathrin Dynamin Infection
    Clathrin-IN-5 (Compound 9) is a Clathrin N-terminal domain-Amphiphysin protein-protein interaction inhibitor with an IC50 of 2.77 μM. Clathrin-IN-5 inhibits the protein-protein interaction between the clathrin N-terminal domain and amphiphysin. Clathrin-IN-5 inhibits clathrin-mediated endocytosis with an IC50 of 4.6 μM. Clathrin-IN-5 inhibits the GTPase activity of Dynamin I with an IC50 of 29.7 μM .
    Clathrin-IN-5
  • HY-186017
    Pitstop 2c

    		Clathrin Infection
    Pitstop 2c is a Clathrin inhibitor with an IC50 of <2 μM. Pitstop 2c binds to Clathrin N-terminal β-propeller domain, inhibits Clathrin function and dynamics and impairs VSV entry. Pitstop 2c inhibits Clathrin-mediated Endocytosis. Pitstop 2d does not inhibit clathrin-independent Endocytosis .
    Pitstop 2c

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