endoperoxide

By Targets:	Dihydroorotate Dehydrogenase (1) DNA/RNA Synthesis (1) Fluorescent Dye (2) Prostaglandin Receptor (5) Reactive Oxygen Species (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (3) Endocrinology (2) Inflammation/Immunology (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W011664

1,3-Diphenylisobenzofuran 4 Publications Verification DPBF	Fluorescent Dye Reactive Oxygen Species	Others
1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .

HY-A0221

Ridogrel R 68070	Prostaglandin Receptor	Inflammation/Immunology
Ridogrel (R 68070) is an orally active combined thromboxane A2 synthetase inhibitor and thromboxane A2/prostaglandin endoperoxide receptor blocker. Ridogrel is potent antiplatelet agent. Anti-inflammatory activities .

HY-N10226

Thielavin B	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously .

HY-100297

MK-447	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH₂, and other prostaglandins.

HY-118895

L-641953	Prostaglandin Receptor	Cardiovascular Disease
L-641953 is an orally active, selective TXA/PG-END receptor (thromboxane-prostaglandin endoperoxide receptor) antagonist. L-641953 significantly inhibits arachidonic acid-induced bronchoconstriction. L-641953 may be used in cardiovascular disease research .

HY-101813

Laflunimus HR325	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Prostaglandin Receptor	Inflammation/Immunology
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC₅₀ values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a *prostaglandin endoperoxide* H synthase (PGHS) -1** and -2 inhibitor .

HY-137227

15(R)-PTA2 15(R)-Pinanethromboxane A2	Others	Cardiovascular Disease
15(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase .

HY-D0034

9,10-Anthracenediyl-bis(methylene)dimalonic acid ABMDMA	Fluorescent Dye	Cancer
9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a biological dye and indicator used to detect singlet oxygen generation (SOG). 9,10-Anthracenediyl-bis(methylene)dimalonic acid is water-soluble derivative of anthracene. 9,10-Anthracenediyl-bis(methylene)dimalonic acid can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease of absorbance at 400 nm .

Cat. No.	Product Name	Type

HY-W011664

1,3-Diphenylisobenzofuran 4 Publications Verification DPBF	Fluorescent Dyes/Probes
1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .

1,3-Diphenylisobenzofuran

4 Publications Verification

DPBF

Fluorescent Dyes/Probes

1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .

HY-D0034

9,10-Anthracenediyl-bis(methylene)dimalonic acid ABMDMA	Dyes
9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a biological dye and indicator used to detect singlet oxygen generation (SOG). 9,10-Anthracenediyl-bis(methylene)dimalonic acid is water-soluble derivative of anthracene. 9,10-Anthracenediyl-bis(methylene)dimalonic acid can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease of absorbance at 400 nm .

9,10-Anthracenediyl-bis(methylene)dimalonic acid

ABMDMA

Dyes

9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a biological dye and indicator used to detect singlet oxygen generation (SOG). 9,10-Anthracenediyl-bis(methylene)dimalonic acid is water-soluble derivative of anthracene. 9,10-Anthracenediyl-bis(methylene)dimalonic acid can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease of absorbance at 400 nm .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10226

Thielavin B	Cardiovascular Disease Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Disease Research Fields	Prostaglandin Receptor
Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously .

Cat. No.	Product Name	Application	Reactivity

HY-P80091

COX2/Cyclooxygenase 2 Antibody PTGS2; COX 2; COX2; COX-2; Cyclooxygenase; Cyclooxygenase2; Cyclooxygenase-2; hCox 2; PGG/HS; PGH synthase 2; PGHS 2; PGHS2; PHS 2; PHS II; PHS2 ; Prostaglandin endoperoxide synthase 2; Prostaglandin G/H synthase 2 precursor; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; TIS10II; PGH2_HUMAN.	WB, ICC/IF, IHC-P	Human, Rat
COX2/Cyclooxygenase 2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 69 kDa, targeting to COX2/Cyclooxygenase 2. It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Rat.

HY-P82792

Cyclooxygenase 1 Antibody (YA2537) PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat

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Fluorescent Dye

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