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  2. 1,3-Diphenylisobenzofuran

1,3-Diphenylisobenzofuran (Synonyms: DPBF)

Cat. No.: HY-W011664 Purity: ≥95.0%
Handling Instructions

1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe which possesses a highly specific reactivity towards singlet oxygen (1O2) forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran can detect the generation of reactive oxygen species (ROS).

For research use only. We do not sell to patients.

1,3-Diphenylisobenzofuran Chemical Structure

1,3-Diphenylisobenzofuran Chemical Structure

CAS No. : 5471-63-6

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Description

1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe which possesses a highly specific reactivity towards singlet oxygen (1O2) forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran can detect the generation of reactive oxygen species (ROS)[1][2].

Molecular Weight

270.33

Formula

C₂₀H₁₄O

CAS No.

5471-63-6

SMILES

C1(C2=CC=CC=C2)=C3C=CC=CC3=C(C4=CC=CC=C4)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 5.56 mg/mL (20.57 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (ultrasonic) (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6992 mL 18.4959 mL 36.9918 mL
5 mM 0.7398 mL 3.6992 mL 7.3984 mL
10 mM 0.3699 mL 1.8496 mL 3.6992 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 0.56 mg/mL (2.07 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 0.56 mg/mL (2.07 mM); Suspended solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

1,3-DiphenylisobenzofuranDPBFOthersROSsingletoxygenendoperoxideInhibitorinhibitorinhibit

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Product Name:
1,3-Diphenylisobenzofuran
Cat. No.:
HY-W011664
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