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fungicidal properties

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (5) Biochemical Assay Reagents (1) Environmental Pollutants (1) Fluorescent Dye (1) Fungal (9) Insecticide (1) Isotope-Labeled Compounds (1) Reference Standards (2)
By Research Areas:	Infection (10)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1539A

Fuchsine base monohydrochloride Magenta base monohydrochloride; Basic Fuchsin monohydrochloride; Rosaniline Base monohydrochloride	Fluorescent Dye Bacterial Fungal	Infection
Fuchsine base (Magenta base; Basic Fuchsin) monohydrochloride is a triaminotriphenylmethane dye. Fuchsine base monohydrochloride has anesthetic, bactericidal and fungicidal properties. Fuchsine base monohydrochloride can be used for the staining of collagen, muscle, mitochondria and tuberculosis. Fuchsine base monohydrochloride is commonly used as a counterstain in Gram staining .

HY-W042181

N-Decyl-N,N-dimethyldecan-1-aminium chloride Didecyldimethylammonium chloride; DDAC	Environmental Pollutants Fungal Bacterial	Infection
N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties .

HY-149601

SDH-IN-8	Fungal	Infection
SDH-IN-8 (compound G40) is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 27 nM for porcine SDH. SDH-IN-8 has fungicidal properties .

HY-149600

SDH-IN-7	Fungal	Infection
SDH-IN-7 (compound G28) is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 26 nM for porcine SDH. SDH-IN-7 has fungicidal properties .

HY-107937

Acrisorcin Akrinol; SCH 7056	Bacterial	Infection
Acrisorcin (Akrinol) serves as a topical anti-infective that is primarily utilized for its fungicidal properties.

HY-126780

Nikkomycin N	Antibiotic Fungal	Infection
Nikkomycin N is a nucleoside antibiotic, which is initially produced by Streptomyces tendae. Nikkomycin N exhibits fungicidal and insecticidal properties through inhibition of chitin synthesis .

HY-169987

bc1 Complex-IN-1	Fungal	Infection
bc1 Complex-IN-1 (compound 12g) is a potent bc1 complex inhibitor. bc1 Complex-IN-1 shows fungicidal properties against Cucumber downy mildew (CDM) .

HY-W042181S

N-Decyl-N,N-dimethyldecan-1-aminium-d6 chloride Didecyldimethylammonium-d6 chloride; DDAC-d6	Isotope-Labeled Compounds Bacterial Fungal	Infection
N-Decyl-N,N-dimethyldecan-1-aminium-d6 (chloride) is a deuterated labeled N-Decyl-N,N-dimethyldecan-1-aminium (chloride) . N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties .

HY-W042181R

N-Decyl-N,N-dimethyldecan-1-aminium chloride (Standard) Didecyldimethylammonium chloride (Standard); DDAC (Standard)	Reference Standards Bacterial Fungal	Infection
N-Decyl-N,N-dimethyldecan-1-aminium (chloride) (Standard) is the analytical standard of N-Decyl-N,N-dimethyldecan-1-aminium (chloride). This product is intended for research and analytical applications. N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties .

HY-W072994

Copper naphthenate	Fungal Insecticide	Infection
Copper naphthenate is an organocopper compound with the properties of a fungicide, preservative, oil-borne protectant, and toxicant. Copper naphthenate increases serum and urine copper levels in exposed populations, causes skin irritation, and induces intraperitoneal toxicity in rats. Copper naphthenate inhibits the growth of decay fungi and molds on moso bamboo, kills the free-living stages of Ichthyophthirius multifiliis, and controls wood-boring insects and termites .

HY-W002105R

2,5-Furandicarboxylic acid (Standard)	Reference Standards Biochemical Assay Reagents	Others
2,5-Furandicarboxylic acid (Standard) is the analytical standard of 2,5-Furandicarboxylic acid (HY-W002105). This product is intended for research and analytical applications. 2,5-Furandicarboxylic acid can be used as the monomer for synthesis of biodegradable polymers such as polyethylene furandicarboxylate (PEF) and polybutylene furandicarboxylate (PBF). 2,5-Furandicarboxylic acid improves the polymers' rigidity, heat resistance and barrier properties, that can be used for food packaging. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, plasticizers, fungicides, macrocyclic ligands and other products.

Cat. No.	Product Name

HY-L938

Antifungal Lead-like compound library	8350 compounds
Currently,the incidence and mortality rates of clinical fungal infections remain high. Existing antifungal drugs are limited in variety and associated with numerous adverse effects, creating an urgent demand for the development of novel antifungal agents. Antifungal compound libraries can support the screening and development of new antifungal drugs. The mechanisms of action of antifungal drugs cover key processes such as fungal cell membrane synthesis, cell wall synthesis, and cell division. They exert fungicidal or fungistatic effects by specifically targeting different molecular pathways. This library includes a variety of core analogs of antifungal drugs, making it adaptable to antifungal research in diverse scenarios. It can be used for the high-throughput screening of novel antifungal drug candidates, enabling the rapid identification of compounds with potential antifungal activity and facilitating the elucidation of drug-target interactions and resistance mechanisms. Additionally, it supports the screening of compounds and combinations that reverse drug resistance, thereby uncovering the novel antifungal potential of existing compounds. The library comprises 8350 compounds with a well-defined screening strategy. The core sources of the compounds include analogs of known antifungal active moleculeswith a similarity score of ≥ 0.6 MCE has collected more than 500 antifungal molecules.All screened compounds conform to lead-like physicochemical properties, exhibiting both structural diversity and drug-like characteristics, and providing valuable support for the research and development of novel antifungal drugs.

Antifungal Lead-like compound library

8350 compounds

Currently,the incidence and mortality rates of clinical fungal infections remain high. Existing antifungal drugs are limited in variety and associated with numerous adverse effects, creating an urgent demand for the development of novel antifungal agents. Antifungal compound libraries can support the screening and development of new antifungal drugs.

The mechanisms of action of antifungal drugs cover key processes such as fungal cell membrane synthesis, cell wall synthesis, and cell division. They exert fungicidal or fungistatic effects by specifically targeting different molecular pathways. This library includes a variety of core analogs of antifungal drugs, making it adaptable to antifungal research in diverse scenarios. It can be used for the high-throughput screening of novel antifungal drug candidates, enabling the rapid identification of compounds with potential antifungal activity and facilitating the elucidation of drug-target interactions and resistance mechanisms. Additionally, it supports the screening of compounds and combinations that reverse drug resistance, thereby uncovering the novel antifungal potential of existing compounds.

The library comprises 8350 compounds with a well-defined screening strategy. The core sources of the compounds include analogs of known antifungal active moleculeswith a similarity score of ≥ 0.6 MCE has collected more than 500 antifungal molecules.All screened compounds conform to lead-like physicochemical properties, exhibiting both structural diversity and drug-like characteristics, and providing valuable support for the research and development of novel antifungal drugs.

Cat. No.	Product Name	Type

HY-B1539A

Fuchsine base monohydrochloride Magenta base monohydrochloride; Basic Fuchsin monohydrochloride; Rosaniline Base monohydrochloride	Fluorescent Dyes
Fuchsine base (Magenta base; Basic Fuchsin) monohydrochloride is a triaminotriphenylmethane dye. Fuchsine base monohydrochloride has anesthetic, bactericidal and fungicidal properties. Fuchsine base monohydrochloride can be used for the staining of collagen, muscle, mitochondria and tuberculosis. Fuchsine base monohydrochloride is commonly used as a counterstain in Gram staining .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-126780

Nikkomycin N	Microorganisms Ketones, Aldehydes, Acids Source Classification	Antibiotic Fungal
Nikkomycin N is a nucleoside antibiotic, which is initially produced by Streptomyces tendae. Nikkomycin N exhibits fungicidal and insecticidal properties through inhibition of chitin synthesis .

HY-W002105R

2,5-Furandicarboxylic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Biochemical Assay Reagents
2,5-Furandicarboxylic acid (Standard) is the analytical standard of 2,5-Furandicarboxylic acid (HY-W002105). This product is intended for research and analytical applications. 2,5-Furandicarboxylic acid can be used as the monomer for synthesis of biodegradable polymers such as polyethylene furandicarboxylate (PEF) and polybutylene furandicarboxylate (PBF). 2,5-Furandicarboxylic acid improves the polymers' rigidity, heat resistance and barrier properties, that can be used for food packaging. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, plasticizers, fungicides, macrocyclic ligands and other products.

Cat. No.	Product Name	Chemical Structure

HY-W042181S

N-Decyl-N,N-dimethyldecan-1-aminium-d6 chloride
N-Decyl-N,N-dimethyldecan-1-aminium-d6 (chloride) is a deuterated labeled N-Decyl-N,N-dimethyldecan-1-aminium (chloride) . N-Decyl-N,N-dimethyldecan-1-aminium chloride (Didecyldimethylammonium chloride) is a dialkyl-quaternary ammonium compound that is used in numerous products for its bactericidal, virucidal and fungicidal properties .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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