Copper naphthenate 

Copper naphthenate is an organocopper compound with the properties of a fungicide, preservative, oil-borne protectant, and toxicant. Copper naphthenate increases serum and urine copper levels in exposed populations, causes skin irritation, and induces intraperitoneal toxicity in rats. Copper naphthenate inhibits the growth of decay fungi and molds on moso bamboo, kills the free-living stages of Ichthyophthirius multifiliis, and controls wood-boring insects and termites^[1][2][3].

Copper naphthenate (1-10 mg/L; 4 h) at 4, 6, 8, or 10 mg/L incubated for 4 h at 23.5 °C kills 100% of Ichthyophthirius multifiliis protomonts, while 1 mg/L has minimal effect and 2 mg/L kills 58.3% of protomonts^[2].
Copper naphthenate (0.3-0.8% (calculated as Cu²⁺ content); 30 min immersion; 30 days fungal incubation) applied via heat-cold impregnation at 0.8% (calculated as Cu²⁺ content) achieves high mould resisting efficacy (85.9%, 94.8%, 70.3%) in Phyllostachys iridescens round bamboo against Aspergillus niger, Penicillium citrinum, and Trichoderma viride, respectively^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

402.03

C₂₀H₃₄CuO₄

1338-02-9

Liquid

CCC1CC(CCC([O-])=O)CC1.CCC2CC(CCC([O-])=O)CC2.[Cu+2]

Room temperature in continental US; may vary elsewhere.

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. Bluhm RE, et al. Increased blood and urine copper after residential exposure to copper naphthenate. J Toxicol Clin Toxicol. 1992;30(1):99-108.

  [2]. Hu GR, et al. In vitro assessment of copper naphthenate against the free-living stages of Ichthyophthirius multifiliis. Aquaculture Reports. 2020 Jul 1;17:100404.
  

  [3]. Jiang J, et al. Enhanced durability of round bamboo treated with copper naphthenate under heat-cold impregnation. Royal Society Open Science. 2022 Nov 1;9(11).