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Results for "

glycerol-3-phosphate dehydrogenase (GPDH) inhibitor

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

2

Natural
Products

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Cat. No. Nom du produit Target Áreas de investigación Chemical Structure
  • HY-116934
    5-Pentadecylresorcinol
    1 Publications Verification

    Adipostatin A

    		 Insecticide Infection Cancer
    5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .
    5-Pentadecylresorcinol
  • HY-121970
    iGP-1

    		Phosphoglycerate Dehydrogenase (PHGDH) Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Metabolic Disease
    iGP-1 is a cell-permeable, selective mixed inhibitor of mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH), with IC50s of 6.3 μM and 13.6 μM for rat mGPDH activity and H2O2 production, respectively. iGP-1 specifically blocks the mitochondrial component of the glycerophosphate shuttle without affecting cytosolic GPDH. iGP-1 not only inhibits cell proliferation and glutaminolysis, and enhances glycolysis, but also significantly alters key cellular physiological processes such as apoptosis, ROS production, HIF-1α stability and mitochondrial membrane potential. iGP-1 remains active in neutrophil cultures under both normoxic and hypoxic conditions, and serves as an ideal probe for glycerol-3-phosphate metabolic mechanisms. iGP-1 has been applied to studies on prostate cancer and related metabolic pathways .
    iGP-1
  • HY-116934R
    5-Pentadecylresorcinol (Standard)

    Adipostatin A (Standard)

    		 Reference Standards Others Infection Cancer
    5-Pentadecylresorcinol (Standard) is the analytical standard of 5-Pentadecylresorcinol. This product is intended for research and analytical applications. 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .
    5-Pentadecylresorcinol (Standard)

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