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immature fruits

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阻害剤およびアゴニスト

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天然物

製品番号 製品名 Target 研究分野 構造式
  • HY-N16391
    (-)-Dihydrojasmonic acid

    (-)-9,10-Dihydrojasmonic acid

    		 Endogenous Metabolite Others
    (-)-Dihydrojasmonic acid ((-)-9,10-Dihydrojasmonic acid) is a compound that can be isolated from the immature fruits of Vicia faba L. and belongs to plant endogenous cyclopentanoid metabolites .
    (-)-Dihydrojasmonic acid
  • HY-N9535A
    (R)-tert-OMe-byakangelicin

    		Drug Metabolite Metabolic Disease
    (R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis .
    (R)-tert-OMe-byakangelicin
  • HY-N19401
    Vescalagin

    		Cholinesterase (ChE) Carbonic Anhydrase Glycosidase JNK p38 MAPK Metabolic Disease Inflammation/Immunology
    Vescalagin is a hexahydroxyphenol. Vescalagin is isolable from Camu-camu (Myrciaria dubia) and immature wax apple fruits. Vescalagin exhibits inhibitory activity against a variety of enzymes, with a Ki value of 5.87 nM against AChE, 3.89 nM against BChE, 11.75 nM against hCA I, 16.23 nM against hCA II, and 16.08 nM against α-glucosidase. Vescalagin inhibits hCA I, hCA II and α-glucosidase in a non-competitive manner. Vescalagin downregulates JNK/p38 MAPK to protect pancreatic β-cells and improve insulin secretion in methylglyoxal-treated rats. Vescalagin reduces hyperglycemia and hypertriglyceridemia in rats fed a high-fructose diet. Vescalagin possesses anti-inflammatory and antioxidant properties .
    Vescalagin

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