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near-infrared fluorophore

" in MedChemExpress (MCE) Product Catalog:

標的別:	Apoptosis (1) Autophagy (1) Fluorescent Dye (11) Tyrosinase (1)
研究分野別:	Cancer (3) Endocrinology (1)
クリックケミストリー:	Tetrazine (1)

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蛍光色素

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製品番号	製品名	Target	研究分野	構造式

HY-D1376

Sulfo-Cyanine5.5 amine potassium	Fluorescent Dye
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.

HY-D2227

IR-58	Autophagy Apoptosis	Cancer
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .

HY-D2219

Sulfo-Cy7 tetrazine	Fluorescent Dye	Others
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

HY-142523

H7	Fluorescent Dye	Cancer
H7 is a second near-infrared (NIR-II) fluorophore .

HY-D1351

Sulfo-Cyanine5.5 maleimide potassium Sulfo-Cy5.5 maleimide potassium	Fluorescent Dye	Others
Sulfo-Cyanine5.5 maleimide (Sulfo-Cy5.5 maleimide) potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .

HY-D2940

SiR-SNAP SiR650-BG	Fluorescent Dye	Others
SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .

HY-D2974

DCI-Ac-HMPC	Fluorescent Dye	Others
DCI-Ac-HMPC is a near-infrared thiol probe. DCI-Ac-HMPC can trigger the intramolecular cascade reaction to in-situ generate NIR coumarin fluorophore. DCI-Ac-HMPC can be used to track the level of thiols .

HY-D1324

Cyanine5.5 hydrazide dichloride	Fluorescent Dye	Others
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λ_ex=684 nm, λ_em=710 nm) .

HY-D3271

IR 750 NHS ester	Fluorescent Dye	Others
IR 750 NHS ester is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and NHS ester reactive group. IR 750 NHS ester can be applied to fluorescent labeling, imaging and detection.

HY-D3270

IR 750 Maleimide	Fluorescent Dye	Others
IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.

HY-D3140

MB-m-borate	Fluorescent Dye Tyrosinase	Cancer
MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research .

HY-D3235

FDOCl-22	Fluorescent Dye	Endocrinology
FDOCl-22 is a HOCl-responsive probe. FDOCl-22 reacts with hypochlorous acid to significantly enhance near-infrared emission and absorption signals, enabling the detection of HOCl levels associated with reagent-induced acute kidney injury. FDOCl-22 can be used in studies related to reagent-induced acute kidney injury .

製品番号	製品名	Type

HY-D1376

Sulfo-Cyanine5.5 amine potassium	蛍光色素
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.

Sulfo-Cyanine5.5 amine potassium

蛍光色素

Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.

HY-D2227

IR-58	蛍光色素
IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway .

HY-D2219

Sulfo-Cy7 tetrazine	蛍光色素
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

HY-D1351

Sulfo-Cyanine5.5 maleimide potassium Sulfo-Cy5.5 maleimide potassium	蛍光色素
Sulfo-Cyanine5.5 maleimide (Sulfo-Cy5.5 maleimide) potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .

HY-D2940

SiR-SNAP SiR650-BG	蛍光色素
SiR-SNAP (SiR650-BG) is a SiR-labeled SNAP tag near-infrared fluorescent probe (Ex/Em: 645 nm/661 nm). SiR-SNAP combines excellent optical properties, good cell membrane permeability, and environmentally sensitive fluorescence characteristics, providing a powerful tool for the dynamic study of proteins in living cells .

HY-D2974

DCI-Ac-HMPC	蛍光色素
DCI-Ac-HMPC is a near-infrared thiol probe. DCI-Ac-HMPC can trigger the intramolecular cascade reaction to in-situ generate NIR coumarin fluorophore. DCI-Ac-HMPC can be used to track the level of thiols .

HY-D1324

Cyanine5.5 hydrazide dichloride	蛍光色素
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λ_ex=684 nm, λ_em=710 nm) .

HY-D3271

IR 750 NHS ester	蛍光色素
IR 750 NHS ester is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and NHS ester reactive group. IR 750 NHS ester can be applied to fluorescent labeling, imaging and detection.

HY-D3270

IR 750 Maleimide	蛍光色素
IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.

HY-D3140

MB-m-borate	蛍光色素
MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research .

MB-m-borate

蛍光色素

MB-m-borate is a double-locked near-infrared fluorescence-activated probe (Ex/Em ≈ 647 nm/684 nm). MB-m-borate undergoes cascade activation by hydrogen peroxide and tyrosinase to release the fluorophore methylene blue, thereby generating a fluorescence activation response. MB-m-borate enables precise detection of melanoma in melanoma cells and mouse models. MB-m-borate can be used for melanoma research .

HY-D3235

FDOCl-22	蛍光色素
FDOCl-22 is a HOCl-responsive probe. FDOCl-22 reacts with hypochlorous acid to significantly enhance near-infrared emission and absorption signals, enabling the detection of HOCl levels associated with reagent-induced acute kidney injury. FDOCl-22 can be used in studies related to reagent-induced acute kidney injury .

製品番号	製品名		Classification

HY-D2219

Sulfo-Cy7 tetrazine		Tetrazine
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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