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  3. IR 750 Maleimide

IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.

For research use only. We do not sell to patients.

IR 750 Maleimide

IR 750 Maleimide Chemical Structure

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Description

IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.

In Vitro

Maleimide is the most popular sulfhydryl-reactive reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1137.36

Formula

C54H64N4O15S4

SMILES

C[N+](C(C=C1)=C2C=C1S(=O)([O-])=O)=C(C2(CCCS(=O)(O)=O)C)/C=C/C3=C(/C(CCC3)=C/C=C4N(C5=C(C/4(CCCS(=O)(O)=O)C)C=C(C=C5)S(=O)(O)=O)C)C6=CC=C(C=C6)CCCCC(NCCCN7C(C=CC7=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
IR 750 Maleimide
Cat. No.:
HY-D3270
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