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Results for "

rat ovarian aromatase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cytochrome P450 (12) Isotope-Labeled Compounds (5) Reference Standards (1)
By Research Areas:	Cancer (10) Cardiovascular Disease (2) Endocrinology (8)

Inhibitors & Agonists

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13632

Exemestane 5+ Cited Publications FCE 24304; EXE	Cytochrome P450	Endocrinology Cancer
Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and **rat ovarian aromatase**, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-113986

Dexfadrostat (R)-Fadrozole; (R)-CGS 16949A free base; FAD286	Cytochrome P450	Cardiovascular Disease
Dexfadrostat ((R)-Fadrozole) is an orally active and selective aromatase inhibitor, with human aromatase IC₅₀ values of 6.4 nM. Dexfadrostat suppresses estrogen synthesis, reduces circulating estradiol levels and suppresses aldosterone production. Dexfadrostat can be used for the research of breast cancer, primary aldosteronism, and hypertension .

HY-13632R

Exemestane (Standard) 5+ Cited Publications FCE 24304(Standard); EXE (Standard)	Cytochrome P450 Reference Standards	Endocrinology Cancer
Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and **rat ovarian aromatase**, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-123247

LY113174	Cytochrome P450	Endocrinology
LY113174 is an orally active *aromatase* inhibitor (IC₅₀ = 24 nM). LY113174 blocks testosterone induced increase in uterine weight in rat, and inhibits ovarian estrogen biosynthesis .

HY-13632S

Exemestane-d2 FCE 24304-d₂; EXE-d₂	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S2

Exemestane-d3 FCE 24304-d₃; EXE-d₃	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane-d₃ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S1

Exemestane-13C3 FCE 24304-¹³C₃; EXE-¹³C₃	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane- ¹³C₃ is the ¹³C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S6

Exemestane-d4 FCE 24304-d₄; EXE-d₄	Isotope-Labeled Compounds Cytochrome P450	Endocrinology Cancer
Exemestane-d₄ (FCE 24304-d₄) is deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and **rat ovarian aromatase**, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S5

Exemestane-13C,d2 FCE 24304-¹³C,d₂; EXE-¹³C,d₂	Cytochrome P450 Isotope-Labeled Compounds	Endocrinology Cancer
Exemestane- ¹³C,d₂ is ¹³C and deuterated labeled Exemestane (HY-13632). Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and **rat ovarian aromatase**, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-W393057

(S)-Aminoglutethimide	Cytochrome P450	Cancer
(S)-Aminoglutethimide is an *aromatase* inhibitor. (S)-Aminoglutethimide has an IC₅₀ value of 23.15 μM for rat ovarian microsomal aromatase. (S)-Aminoglutethimide can be used in the research of diseases such as breast cancer .

HY-113986C

Dexfadrostat hydrochloride (R)-Fadrozole hydrochloride; (R)-CGS 16949A; FAD286 hydrochloride	Cytochrome P450	Cardiovascular Disease Cancer
Dexfadrostat ((R)-Fadrozole) hydrochloride is an orally active and selective aromatase inhibitor, with human aromatase IC₅₀ values of 6.4 nM. Dexfadrostat hydrochloride suppresses estrogen synthesis, reduces circulating estradiol levels and suppresses aldosterone production. Dexfadrostat hydrochloride can be used for the research of breast cancer, primary aldosteronism, and hypertension .

HY-123500

CGP-45688	Cytochrome P450	Cancer
CGP-45688 is an orally active non-steroidal aromatase inhibitor with an ED₅₀ of 30-100 μg/kg. CGP-45688 can reduce the level of estrogen in the body, thereby inhibiting the growth of estrogen-dependent tumors. CGP-45688 inhibits the growth of estrogen-dependent breast tumors in rat models. CGP-45688 disrupts the ovarian cycle and inhibits the weight of the uterus. CGP-45688 can be used for the study of breast cancer .

Cat. No.	Product Name	Chemical Structure

HY-13632S

Exemestane-d2
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S2

Exemestane-d3
Exemestane-d₃ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S1

Exemestane-13C3
Exemestane- ¹³C₃ is the ¹³C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S6

Exemestane-d4
Exemestane-d₄ (FCE 24304-d₄) is deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and **rat ovarian aromatase**, respectively. Exemestane can be used for hormone-dependent breast cancer research .

HY-13632S5

Exemestane-13C,d2
Exemestane- ¹³C,d₂ is ¹³C and deuterated labeled Exemestane (HY-13632). Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal *aromatase* inhibitor with IC₅₀s of 30 nM and 40 nM for human placental and **rat ovarian aromatase**, respectively. Exemestane can be used for hormone-dependent breast cancer research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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