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  2. Aromatase
  3. Exemestane-D2

Exemestane-D2 (Synonyms: FCE 24304-D2; EXE-D2)

Cat. No.: HY-13632S
Handling Instructions

Exemestane-D2 (FCE 24304-D2) is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research.

For research use only. We do not sell to patients.

Exemestane-D2 Chemical Structure

Exemestane-D2 Chemical Structure

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1 mg USD 190 Ask For Quote & Lead Time
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Description

Exemestane-D2 (FCE 24304-D2) is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

298.42

Formula

C20H22D2O2

SMILES

C[[email protected]@]12[[email protected]]3([H])[[email protected]](CC(C1=CC(C=C2)=O)=C)([H])[[email protected]@]4([H])[[email protected]](CC3)(C(C([2H])([2H])C4)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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