1. Others Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds Cytochrome P450
  3. Exemestane-13C3

Exemestane-13C3 is the 13C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

For research use only. We do not sell to patients.

Exemestane-<sup>13</sup>C<sub>3</sub> Chemical Structure

Exemestane-13C3 Chemical Structure

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Description

Exemestane-13C3 is the 13C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

IC50 & Target

Aromatase

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

296.36

Formula

C1713C3H21O2

SMILES

C[C@]1([C@](CC2)([H])[C@]3([H])CC(C4=[13C][13C](C=C[C@]4(C)[C@@]3([H])CC1)=O)=[13C])C2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Exemestane-13C3
Cat. No.:
HY-13632S1
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