Search Result

Results for "

tissue-nonspecific alkaline phosphatase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phosphatase (3) Drug Derivative (1) Drug Intermediate (1)
By Research Areas:	Cardiovascular Disease (2) Inflammation/Immunology (2)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended: Phosphatase SHP2 PhosTACs PTEN SHP1

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-124756

SBI-425 3 Publications Verification	Phosphatase	Cardiovascular Disease
SBI-425 is an orally active and potent TNAP (tissue-nonspecific **alkaline phosphatase) inhibitor (IC₅₀**=16 nM). SBI-425 inhibits TNAP in the vasculature, improving cardiovascular parameters and survival .

HY-14210

TNAP-IN-1	Phosphatase	Inflammation/Immunology
TNAP-IN-1 (Compound 1) is a selective tissue-nonspecific alkaline phosphatase (TNAP) inhibitor, with an IC₅₀ of 0.19 μM. TNAP-IN-1 can be used for the research of soft tissue calcification .

HY-78144

4-Methylsalicylic acid	Drug Derivative Drug Intermediate	Inflammation/Immunology
4-Methylsalicylic acid is a methyl derivative of Salicylic acid (HY-B0167). 4-Methylsalicylic acid derivatives inhibit the activity of alkaline phosphatases such as TNAP and IAP. 4-Methylsalicylic acid derivatives exhibit immunosuppressive activity .

HY-P991210

Efzimfotase alfa ALXN-1850	Phosphatase	Cardiovascular Disease
Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .

Cat. No.	상품명	Target	Research Area	Image

HY-P991210

Efzimfotase alfa ALXN-1850	Phosphatase	Cardiovascular Disease
Efzimfotase alfa (ALXN-1850) is enzyme replacement therapy agent targeting the deficiency of tissue-nonspecific alkaline phosphatase (TNSALP). Efzimfotase alfa functions by hydrolyzing the substrates of TNSALP, reducing the concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5′-phosphate (PLP). Efzimfotase alfa is promising for research of hypophosphatasia (HPP) .

Species:	Human (2)
Tag:	His (2)
Source:	HEK293 (2)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P7880

	Alkaline Phosphatase/ALPL Protein, Human (HEK293, His) rHualkaline phosphatase, tissue-nonspecific isozyme/ALPL, His; alkaline phosphatase; tissue-nonspecific Isozyme; AP-TNAP; TNSALP; alkaline phosphatase Liver/Bone/Kidney Isozyme; ALPL	Human	HEK293
	Alkaline Phosphatase/ALPL Protein, Human (HEK 293, His) is a cell-surface homodimeric phosphohydrolase that is richly expressed in the skeleton, liver, kidney and developing teeth.

HY-P704350

	HRP-Labeled Alkaline Phosphatase/ALPL Protein, Human (HEK293, His) rHualkaline phosphatase, tissue-nonspecific isozyme/ALPL, His; alkaline phosphatase; tissue-nonspecific Isozyme; AP-TNAP; TNSALP; alkaline phosphatase Liver/Bone/Kidney Isozyme; ALPL	Human	HEK293
	HRP-Labeled Alkaline Phosphatase/ALPL Protein, Human (HEK293, His) is the recombinant human-derived HRP-Labeled Alkaline Phosphatase/ALPL protein, expressed by HEK293, with C-His tag.

Compare Products


Products	해외재고보유 - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P86653

	Alkaline phosphatase Antibody (YA6345) ALPL; AKP2; alkaline phosphatase liver/bone/kidney; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase tissue nonspecific isozyme; AP TNAP; AP-TNAP; APTNAP; BALP; BAP; FLJ40094; FLJ93059; Glycerophosphatase; HOPS; Liver/bone/kidney isozyme; Liver/bone/kidney type alkaline phosphatase; MGC161443; MGC167935; PHOA; PPBT_HUMAN; tissue non specific alkaline phosphatase; tissue nonspecific ALP; TNAP; TNSALP.	WB	Human, Mouse, Rat
	Alkaline phosphatase Antibody (YA6345) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Alkaline phosphatase.

HY-P86653A

	Alkaline phosphatase Antibody (YA6345)(PBS only) ALPL; AKP2; alkaline phosphatase liver/bone/kidney; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase tissue nonspecific isozyme; AP TNAP; AP-TNAP; APTNAP; BALP; BAP; FLJ40094; FLJ93059; Glycerophosphatase; HOPS; Liver/bone/kidney isozyme; Liver/bone/kidney type alkaline phosphatase; MGC161443; MGC167935; PHOA; PPBT_HUMAN; tissue non specific alkaline phosphatase; tissue nonspecific ALP; TNAP; TNSALP.	WB	Human, Mouse, Rat
	Alkaline phosphatase Antibody (YA6345) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Alkaline phosphatase.

Compare Products


Products	해외재고보유 - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

온라인 문의

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
호칭			Country or Region *
고객명 *			회사명 *
Department *
메일주소 *			상품명 *
Cat. No.			Requested quantity *
전화번호 *
비고

온라인 문의

Inquiry Information

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
이메일 *

	Sorry, but the email address you supplied was invalid.