TNAP-IN-1
Based on 1 Customer Validation
TNAP-IN-1 (Compound 1) is a selective tissue-nonspecific alkaline phosphatase (TNAP) inhibitor, with an IC50 of 0.19 μM. TNAP-IN-1 can be used for the research of soft tissue calcification.
For research use only. We do not sell to patients.
- Purity: 98.54%
- CAS No.: 496014-13-2
- Formula: C17H16N2O4S
- Molecular Weight:344.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Metabolism/Protease Compound Library
HY-L012
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Clinical Compound Library
HY-L026
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Drug Repurposing Compound Library
HY-L035
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Phosphatase Inhibitor Library
HY-L081
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Metabolic Enzyme Compound Library
HY-L146
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Highly Selective Inhibitors Library
HY-L158
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Drug Repurposing Compound Library Plus
HY-L035P
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Clinical Compound Library Plus
HY-L026P
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-1 | IC50 |
0.19 μM
Compound: 1, pubchem CID 2931238
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Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay
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[PMID: 19821572] |
Chemical Information
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CAS No. 496014-13-2
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Appearance Solid
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Molecular Weight 344.38
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Formula C17H16N2O4S
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Color Light yellow to yellow
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SMILES
O=S(NC1=CN=C2C=CC=CC2=C1)(C3=CC(OC)=CC=C3OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (145.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9038 mL | 14.5188 mL | 29.0377 mL | 72.5942 mL |
| 5 mM | 0.5808 mL | 2.9038 mL | 5.8075 mL | 14.5188 mL | |
| 10 mM | 0.2904 mL | 1.4519 mL | 2.9038 mL | 7.2594 mL | |
| 15 mM | 0.1936 mL | 0.9679 mL | 1.9358 mL | 4.8396 mL | |
| 20 mM | 0.1452 mL | 0.7259 mL | 1.4519 mL | 3.6297 mL | |
| 25 mM | 0.1162 mL | 0.5808 mL | 1.1615 mL | 2.9038 mL | |
| 30 mM | 0.0968 mL | 0.4840 mL | 0.9679 mL | 2.4198 mL | |
| 40 mM | 0.0726 mL | 0.3630 mL | 0.7259 mL | 1.8149 mL | |
| 50 mM | 0.0581 mL | 0.2904 mL | 0.5808 mL | 1.4519 mL | |
| 60 mM | 0.0484 mL | 0.2420 mL | 0.4840 mL | 1.2099 mL | |
| 80 mM | 0.0363 mL | 0.1815 mL | 0.3630 mL | 0.9074 mL | |
| 100 mM | 0.0290 mL | 0.1452 mL | 0.2904 mL | 0.7259 mL |
TNAP-IN-1 Related Classifications
HY-14210 Related Classifications
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