TNAP-IN-1
Based on 1 Customer Validation
TNAP-IN-1 (Compound 1) is a selective tissue-nonspecific alkaline phosphatase (TNAP) inhibitor, with an IC50 of 0.19 μM. TNAP-IN-1 can be used for the research of soft tissue calcification.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.54%
- CAS 番号: 496014-13-2
- 分子式: C17H16N2O4S
- 分子量:344.38
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Metabolism/Protease Compound Library
HY-L012
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Clinical Compound Library
HY-L026
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Drug Repurposing Compound Library
HY-L035
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Phosphatase Inhibitor Library
HY-L081
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Metabolic Enzyme Compound Library
HY-L146
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Highly Selective Inhibitors Library
HY-L158
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Drug Repurposing Compound Library Plus
HY-L035P
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Clinical Compound Library Plus
HY-L026P
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-1 | IC50 |
0.19 μM
Compound: 1, pubchem CID 2931238
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Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay
Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assay
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[PMID: 19821572] |
化学情報
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CAS 番号 496014-13-2
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性状 Solid
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分子量 344.38
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分子式 C17H16N2O4S
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Color Light yellow to yellow
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SMILES
O=S(NC1=CN=C2C=CC=CC2=C1)(C3=CC(OC)=CC=C3OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (145.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9038 mL | 14.5188 mL | 29.0377 mL | 72.5942 mL |
| 5 mM | 0.5808 mL | 2.9038 mL | 5.8075 mL | 14.5188 mL | |
| 10 mM | 0.2904 mL | 1.4519 mL | 2.9038 mL | 7.2594 mL | |
| 15 mM | 0.1936 mL | 0.9679 mL | 1.9358 mL | 4.8396 mL | |
| 20 mM | 0.1452 mL | 0.7259 mL | 1.4519 mL | 3.6297 mL | |
| 25 mM | 0.1162 mL | 0.5808 mL | 1.1615 mL | 2.9038 mL | |
| 30 mM | 0.0968 mL | 0.4840 mL | 0.9679 mL | 2.4198 mL | |
| 40 mM | 0.0726 mL | 0.3630 mL | 0.7259 mL | 1.8149 mL | |
| 50 mM | 0.0581 mL | 0.2904 mL | 0.5808 mL | 1.4519 mL | |
| 60 mM | 0.0484 mL | 0.2420 mL | 0.4840 mL | 1.2099 mL | |
| 80 mM | 0.0363 mL | 0.1815 mL | 0.3630 mL | 0.9074 mL | |
| 100 mM | 0.0290 mL | 0.1452 mL | 0.2904 mL | 0.7259 mL |
TNAP-IN-1 関連分類
HY-14210 関連分類
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