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uric acid excretion

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153972
    URAT1&XO inhibitor 2

    		URAT1 Xanthine Oxidase Metabolic Disease Inflammation/Immunology
    URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia .
    URAT1&XO inhibitor 2

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