2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. SFTI-1

SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms.

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SFTI-1

SFTI-1 構造式

CAS 番号 : 245080-24-4

容量 価格（税別） 在庫状況 数量
5 mg $310 在庫あり
10 mg $500 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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SFTI-1 関連抗体

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  • 生物活性

  • 純度とドキュメンテーション

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製品説明

SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms[1][2].

体外実験

SFTI-1 (0-400 nM; 2 h) shows a Ki of 0.5 nM for bovine β-trypsin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SFTI-1 関連抗体
分子量

1513.78

分子式

C67H104N18O18S2
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Cyclic(Arg-Cys-Thr-Lys-Ser-Ile-Pro-Pro-Ile-Cys-Phe-Pro-Asp-Gly) (Disulfide bridge: Cys2-Cys10)
Sequence Shortening

Cyclic(RCTKSIPPICFPDG) (Disulfide bridge: Cys2-Cys10)
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : ≥ 100 mg/mL (66.06 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6606 mL 3.3030 mL 6.6060 mL
5 mM 0.1321 mL 0.6606 mL 1.3212 mL
10 mM 0.0661 mL 0.3303 mL 0.6606 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 99.60%

COA (268 KB) LCMS (87 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6606 mL 3.3030 mL 6.6060 mL 16.5149 mL
5 mM 0.1321 mL 0.6606 mL 1.3212 mL 3.3030 mL
10 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6515 mL
15 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1010 mL
20 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
25 mM 0.0264 mL 0.1321 mL 0.2642 mL 0.6606 mL
30 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5505 mL
40 mM 0.0165 mL 0.0826 mL 0.1651 mL 0.4129 mL
50 mM 0.0132 mL 0.0661 mL 0.1321 mL 0.3303 mL
60 mM 0.0110 mL 0.0550 mL 0.1101 mL 0.2752 mL
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SFTI-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SFTI-1245080-24-4SFTI1SFTI 1Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasescyclic trypsin inhibitor Bowman-BirkInhibitorinhibitorinhibit

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製品名:
SFTI-1
製品番号:
HY-P10033
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