245080-24-4
Chemical Structure
SFTI-1
- CAS No.: 245080-24-4
- Formula:C67H104N18O18S2
- Molecular Weight:1513.78
InChIKey: QQBRBPSSMDPLLA-GECFALDLSA-N
SMILES: O=C(N(CCC1)[C@]1([H])C(N[C@@](C(N[C@](CSSC[C@@](NC([C@@H](NC2=O)CCCNC(N)=N)=O)([H])C3=O)([H])C(N[C@H](C(N4[C@@](C(N[C@H](C(NC2)=O)CC(O)=O)=O)([H])CCC4)=O)CC5=CC=CC=C5)=O)=O)([H])[C@@H](C)CC)=O)[C@@](CCC6)([H])N6C([C@](NC([C@@H](NC([C@@H](NC([C@](N3)([H])[C@H](O)C)=O)CCCCN)=O)CO)=O)([H])[C@@H](C)CC)=O
Biological Activity: SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms[1][2].
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SFTI-1 | 99.15% | SFTI-1 is a cyclic peptide trypsin inhibitor consisting of 14 amino acid residues. SFTI-1 belongs to the Bowman-Birk class of inhibitors. Characterized by its small size, high stability, and potent activity, SFTI-1 can be used for research on peptide drug design platforms. | ||||||||||||||||||||
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References
- [1]. M L Korsinczky, et al. Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant. J Mol Biol. 2001 Aug 17;311(3):579-91. [Content Brief]
- [2]. Korsinczky ML, et al. Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1. Biochemistry. 2005 Feb 1;44(4):1145-53. [Content Brief]
