1. Epigenetics
  2. Small Interfering RNA (siRNA)
  3. SiRNA Negative Control

SiRNA Negative Control is a siRNA of 21 nucleotides, and can be used as a negative control. SiRNA Negative Control has no homology to most known gene sequence. SiRNA Negative Control can be used in human, mouse and rat cells in vitro. SiRNA Negative Control can be used as experimental control benchmark, verification of experimental reliability and standardization reference. SiRNA Negative Control is a common negative control used in most research articles.

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Based on 21 publication(s) in Google Scholar

Other Forms of SiRNA Negative Control:

Top Publications Citing Use of Products

    SiRNA Negative Control purchased from MedChemExpress. Usage Cited in: Mol Med. 2025 Sep 29;31(1):307.  [Abstract]

    SiRNA Negative Control (Si-NC)- or si-Miro1-transfected mGFP-EPO-BM-MSCs (showing a green fluorescence) were co-cultured with mtCC1-2 cells labeled with CellTrace Violet (showing a blue fluorescence). Flow cytometry analyzed the percentage of mtCC1-2 cells labeled with GFP and CellTrace Violet.

    SiRNA Negative Control purchased from MedChemExpress. Usage Cited in: Mol Med. 2025 Sep 29;31(1):307.  [Abstract]

    Immunoblotting of M-sec in SiRNA Negative Control (Si-NC)- or si-M-sec-transfected EPO-BM-MSCs.

    SiRNA Negative Control purchased from MedChemExpress. Usage Cited in: Mol Med. 2025 Sep 29;31(1):307.  [Abstract]

    Fluorescence microscopy and the percentage of TNT-forming cells between SiRNA Negative Control (si-NC)-transfected EPO-BM-MSCs or si-M-sec-transfected EPO-BM-MSCs.

    SiRNA Negative Control purchased from MedChemExpress. Usage Cited in: Ann Hepatol. 2025 Jan 3:101776.  [Abstract]

    Expression of PFKM mRNA transcript in MHCC97 and Huh-7 HCC cells transfected with SiRNA Negative Control (si-NC) or si-METTL16 (the 1:1 ratio mix of si-METTL16#1:si-METTL16#3) by quantitative PCR (n = 3).

    SiRNA Negative Control purchased from MedChemExpress. Usage Cited in: Ann Hepatol. 2025 Jan 3:101776.  [Abstract]

    SiRNA Negative Control (si-NC) (48 h). CCK-8 cell viability assay in transfected MHCC97 and Huh-7 HCC cells.
    • Activité biologique

    • Pureté et documentation

    • Avis client

    Description

    SiRNA Negative Control is a siRNA of 21 nucleotides, and can be used as a negative control. SiRNA Negative Control has no homology to most known gene sequence. SiRNA Negative Control can be used in human, mouse and rat cells in vitro. SiRNA Negative Control can be used as experimental control benchmark, verification of experimental reliability and standardization reference. SiRNA Negative Control is a common negative control used in most research articles.

    In Vitro

    SiRNA Negative Control is a siRNA of 21 nucleotides, and can be used as a negative control. SiRNA Negative Control has no homology to most known gene sequence. SiRNA Negative Control can be used in human, mouse and rat cells in vitro. SiRNA Negative Control can be used as experimental control benchmark, verification of experimental reliability and standardization reference. SiRNA Negative Control is a common negative control used in most research articles.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Masse moléculaire

    13323.03

    Appearance

    Solid

    Color

    White to off-white

    SMILES

    [RNA, (UUCUCCGAACGUGUCACGUUU), complex with RNA, (ACGUGACACGUUCGGAGAAUU) (1:1)]

    Livraison

    Room temperature in continental US; may vary elsewhere.

    Stockage

    -20°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvant et solubilité
    In Vitro: 

    H2O : 100 mg/mL (7.51 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 0.0751 mL 0.3753 mL 0.7506 mL
    5 mM 0.0150 mL 0.0751 mL 0.1501 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Calculateur de molarité

    • Calculateur de dilution

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Pureté et documentation

    Purity: 99.24%

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 0.0751 mL 0.3753 mL 0.7506 mL 1.8764 mL
    5 mM 0.0150 mL 0.0751 mL 0.1501 mL 0.3753 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Nom du produit:
    SiRNA Negative Control
    Cat. No.:
    HY-150150
    Quantité:
    MCE Japan Authorized Agent: