Tetraglycine hydrochloride

Cat. No.: HY-W142467A: Fiche technique
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Instruction de manipulation
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Tetraglycine hydrochloride is a oligopeptide composed of four glycine monomers.

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Tetraglycine hydrochloride Chemical Structure

CAS No. : 38126-71-5

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Other In-stock Forms of Tetraglycine hydrochloride:

Tetraglycine

Other Forms of Tetraglycine hydrochloride:

Tetraglycine In-stock

Recommandations en vedette

•Related Small Molecules:

•Related Proteins:

Activité biologique
Pureté et documentation
Références
Avis client

Description

Tetraglycine hydrochloride is a oligopeptide composed of four glycine monomers^[1].

In Vivo

Tetraglycine and Triglycine (1.0 μmol glycine/g body wt (246.22 mg/kg), injected into a central vein) results in greater glycine concentration in the kidney than injection of either Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) or Diglycine^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Sprague-Dawley rats (270-300 g)^[1]
Dosage:	1.0 μmol glycine/g body wt (246.22 mg/kg)
Administration:	IV, injected over a period of 30 s
Result:	Five minutes after the Tetraglycine injection, there were accumulations of diglvcine, triglvcine, and Tetraglycine in the kidney.

Masse moléculaire

282.68

Formule

C₈H₁₅ClN₄O₅

CAS No.

38126-71-5

Appearance

Solid

Color

White to off-white

Sequence Shortening

GGGG

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvant et solubilité

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Pureté et documentation

Purity: 99.19%

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Fiche technique (265 KB) SDS (252 KB)

COA (243 KB) HNMR (426 KB) LCMS (88 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Adibi SA, et al. Enrichment of glycine pool in plasma and tissues by glycine, di-, tri-, and tetraglycine. Am J Physiol. 1982 Nov;243(5):E413-7. [Content Brief]